Modulation of the arachidonic cascade with omega 3 fatty acids or analogues: Potential therapeutic benefits

peer reviewed Increasing interest in the role of omega 3 fatty acids has arisen in these latest years since evidence of their implication in the cardioprotective fish based diet of the Inuit has been demonstrated. Furthermore, several in vitro, in vivo and epidemiological studies support the benefit...

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Bibliographic Details
Published in:Mini-Reviews in Medicinal Chemistry
Main Authors: Roland, Isabelle, de Leval, X., Evrard, Brigitte, Pirotte, Bernard, Dogné, Jean-Michel, Delattre, Luc
Format: Article in Journal/Newspaper
Language:English
Published: Bentham Science Publ Ltd 2004
Subjects:
omega 3 fatty acid
omega 6/omega 3 ratio
cardiovascular disease
cancer
inflammation
psychiatric disorders
Human health sciences
Pharmacy
pharmacology & toxicology
Physical
chemical
mathematical & earth Sciences
Chemistry
Sciences de la santé humaine
Pharmacie
pharmacologie & toxicologie
Physique
chimie
mathématiques & sciences de la terre
inuit
Online Access:https://orbi.uliege.be/handle/2268/23123
https://doi.org/10.2174/1389557043403738
Description
Summary:peer reviewed Increasing interest in the role of omega 3 fatty acids has arisen in these latest years since evidence of their implication in the cardioprotective fish based diet of the Inuit has been demonstrated. Furthermore, several in vitro, in vivo and epidemiological studies support the benefit of this fatty acids intake in various pathological states such as in the cardiovascular, cancer, inflammation, psychiatric, paediatric, pulmonary, dermatological and ophthalmologic fields. This review will focus on metabolism and pharmacological implication of w3 fatty acids intake as well as its interest in the prevention or treatment of the above-mentioned pathologies.

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