Chlamydia trachomatis in iceland : Prevalence, clinico-epidemiological features and comparison of cobas 480 ct/ng and aptima combo 2 (ct/ng) for diagnosis

Publisher Copyright: © 2021, Medical Journals/Acta D-V. All rights reserved. The aims of this study were to assess the prevalence of, and risk factors for, Chlamydia trachomatis in at-tendees recruited prospectively from October 2018 to January 2019 at the only sexually transmitted infections clinic...

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Bibliographic Details
Published in:Acta Dermato Venereologica
Main Authors: Hilmarsdóttir, Ingibjörg, Arnardóttir, Eva Mjöll, Jóhannesdóttir, Elísabet Reykdal, Golparian, Daniel, Unemo, Magnus
Other Authors: Faculty of Medicine, Clinical Laboratory Services, Diagnostics and Blood Bank, Other departments, Internal Medicine and Emergency Services, Landspitali - The National University Hospital of Iceland
Format: Article in Journal/Newspaper
Language:English
Published: 2021
Subjects:
Kynsjúkdómar
Klamýdía
Ísland
Áhættuþættir
Algengi sjúkdóma
Chlamydia trachomatis
Iceland
Neisseria gonorrhoeae
Nucleic acid amplification
Prevalence
Risk factor
Sexually transmitted disease
Chlamydia trachomatis/genetics
Chlamydia Infections/diagnosis
Humans
Male
Tomography
X-Ray Computed
Sensitivity and Specificity
Female
Gonorrhea/diagnosis
Iceland/epidemiology
Dermatology
Reykjavík
Online Access:https://hdl.handle.net/20.500.11815/2921
https://doi.org/10.2340/00015555-3762
Description
Summary:Publisher Copyright: © 2021, Medical Journals/Acta D-V. All rights reserved. The aims of this study were to assess the prevalence of, and risk factors for, Chlamydia trachomatis in at-tendees recruited prospectively from October 2018 to January 2019 at the only sexually transmitted infections clinic in Iceland (in Reykjavík), and to eva-luate the cobas 4800 CT/NG Test and Aptima Combo 2 Assay for C. trachomatis detection in male urine and female vaginal swabs. Prevalence of C. trachomatis was 15.8% among 487 women and 13.6% among 491 men (no Neisseria gonorrhoeae positive patients were found). C. trachomatis detection was independently and positively associated with being tested for contact tracing, 18–24 years of age, and reporting ≥ 6 sexual partners within 12 months. Reporting sex with non-residents of Iceland was associated with a lower risk of C. trachomatis infection. Both assays had a high sen-sitivity in detection of C. trachomatis (Aptima Combo 2: 100%; cobas 4800 CT/NG: 95.1%) and high speci-ficity (100% and 99.6%, respectively). The high local prevalence of C. trachomatis and increased acquisition risk following sex with residents are of public health concern. Peer reviewed

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