Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort
Publisher's version (útgefin grein) Nordic Nutrition Recommendations (NNR) recommend exclusive breastfeeding until 6 months, partial breastfeeding until 1 year or longer and irrespective of breastfeeding, avoiding solid foods before 4 months. Strong evidence was found for benefits of breastfeed...
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Online Access: | https://hdl.handle.net/20.500.11815/1681 https://doi.org/10.3390/nu11071690 |
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ftopinvisindi:oai:opinvisindi.is:20.500.11815/1681 2023-05-15T16:49:37+02:00 Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort Thorisdottir, Birna Gunnarsdottir, Ingibjorg Viðarsdóttir, Anna Guðrún Sigurðardóttir, Sigurveig Birgisdottir, Bryndis Eva Thorsdottir, Inga Matvæla- og næringarfræðideild (HÍ) Faculty of Food Science and Nutrition (UI) Félagsfræði-, mannfræði- og þjóðfræðideild (HÍ) Faculty of Sociology, Anthropology and Folkloristics (UI) Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) Félagsvísindasvið (HÍ) School of Social Sciences (UI) Háskóli Íslands University of Iceland 2019-07-23 1690 https://hdl.handle.net/20.500.11815/1681 https://doi.org/10.3390/nu11071690 en eng MDPI AG Nutrients;11(7) https://www.mdpi.com/2072-6643/11/7/1690/pdf Thorisdottir, B.; Gunnarsdottir, I.; Vidarsdottir, A.G.; Sigurdardottir, S.; Birgisdottir, B.E.; Thorsdottir, I. Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort. Nutrients 2019, 11, 1690. 2072-6643 https://hdl.handle.net/20.500.11815/1681 Nutrients doi:10.3390/nu11071690 info:eu-repo/semantics/openAccess Breastfeeding Children Complementary feeding IgE sensitization Infants Nordic diet Recommendations Solid food Vitamin D Brjóstagjöf Mataræði Ungbörn D vítamín Tilviksrannsóknir info:eu-repo/semantics/article 2019 ftopinvisindi https://doi.org/20.500.11815/1681 https://doi.org/10.3390/nu11071690 2022-11-18T06:51:54Z Publisher's version (útgefin grein) Nordic Nutrition Recommendations (NNR) recommend exclusive breastfeeding until 6 months, partial breastfeeding until 1 year or longer and irrespective of breastfeeding, avoiding solid foods before 4 months. Strong evidence was found for benefits of breastfeeding regarding growth and infections but limited/inconclusive evidence regarding atopic disease and asthma. Vitamin D is of special interest in the Nordic diet. The aim of this prospective study was to compare infant feeding and vitamin D between immunoglobulin E (IgE) sensitized (n = 14) and non-sensitized (n = 130) children at 6 years. Information on diet and vitamin D supplement use were collected with dietary recall (5 months), 1-d food records (5 and 6 months) and 3-d weighed food records (12 months and 6 years). Serum-specific IgE-antibodies against milk, egg, cod, wheat, soy and peanut (cut-off specific IgE ≥ 0.35 kUA/L) were measured at 6 years and serum 25-hydroxyvitamin D at 12 months and 6 years. At 4 months, 57% of IgE sensitized vs. 23% of non-sensitized children (p 0.01) had received solid food. At 12 months, IgE sensitized children had a lower intake of vitamin D (median (25th, 75th percentiles): 3.9 μg/d (3.2, 7.2) vs. 8.1 μg/d (4.4, 12.3), p = 0.03) and at 6 years, fewer used vitamin D supplements regularly (23% vs. 56%, p = 0.03). Introduction of solid foods prior to 4 months increased the odds of IgE-sensitization, OR = 4.9 (95%, CI = 1.4–16.6) and vitamin D supplement at 6 years decreased the odds of IgE-sensitization, OR = 0.2 (95%, CI = 0.1–0.98), adjusting for maternal smoking. These observations support the NNR in their recommendation against introducing complementary solid foods before the age of 4 months. Furthermore, they support encouraging vitamin D intake for young children at northern latitudes. This study was supported by the University of Iceland with a doctoral grant [HI15120056] and a grant from the University of Iceland Research Fund [2014–2016], Landspitali University Hospital ... Article in Journal/Newspaper Iceland Opin vísindi (Iceland) Nutrients 11 7 1690 |
institution |
Open Polar |
collection |
Opin vísindi (Iceland) |
op_collection_id |
ftopinvisindi |
language |
English |
topic |
Breastfeeding Children Complementary feeding IgE sensitization Infants Nordic diet Recommendations Solid food Vitamin D Brjóstagjöf Mataræði Ungbörn D vítamín Tilviksrannsóknir |
spellingShingle |
Breastfeeding Children Complementary feeding IgE sensitization Infants Nordic diet Recommendations Solid food Vitamin D Brjóstagjöf Mataræði Ungbörn D vítamín Tilviksrannsóknir Thorisdottir, Birna Gunnarsdottir, Ingibjorg Viðarsdóttir, Anna Guðrún Sigurðardóttir, Sigurveig Birgisdottir, Bryndis Eva Thorsdottir, Inga Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort |
topic_facet |
Breastfeeding Children Complementary feeding IgE sensitization Infants Nordic diet Recommendations Solid food Vitamin D Brjóstagjöf Mataræði Ungbörn D vítamín Tilviksrannsóknir |
description |
Publisher's version (útgefin grein) Nordic Nutrition Recommendations (NNR) recommend exclusive breastfeeding until 6 months, partial breastfeeding until 1 year or longer and irrespective of breastfeeding, avoiding solid foods before 4 months. Strong evidence was found for benefits of breastfeeding regarding growth and infections but limited/inconclusive evidence regarding atopic disease and asthma. Vitamin D is of special interest in the Nordic diet. The aim of this prospective study was to compare infant feeding and vitamin D between immunoglobulin E (IgE) sensitized (n = 14) and non-sensitized (n = 130) children at 6 years. Information on diet and vitamin D supplement use were collected with dietary recall (5 months), 1-d food records (5 and 6 months) and 3-d weighed food records (12 months and 6 years). Serum-specific IgE-antibodies against milk, egg, cod, wheat, soy and peanut (cut-off specific IgE ≥ 0.35 kUA/L) were measured at 6 years and serum 25-hydroxyvitamin D at 12 months and 6 years. At 4 months, 57% of IgE sensitized vs. 23% of non-sensitized children (p 0.01) had received solid food. At 12 months, IgE sensitized children had a lower intake of vitamin D (median (25th, 75th percentiles): 3.9 μg/d (3.2, 7.2) vs. 8.1 μg/d (4.4, 12.3), p = 0.03) and at 6 years, fewer used vitamin D supplements regularly (23% vs. 56%, p = 0.03). Introduction of solid foods prior to 4 months increased the odds of IgE-sensitization, OR = 4.9 (95%, CI = 1.4–16.6) and vitamin D supplement at 6 years decreased the odds of IgE-sensitization, OR = 0.2 (95%, CI = 0.1–0.98), adjusting for maternal smoking. These observations support the NNR in their recommendation against introducing complementary solid foods before the age of 4 months. Furthermore, they support encouraging vitamin D intake for young children at northern latitudes. This study was supported by the University of Iceland with a doctoral grant [HI15120056] and a grant from the University of Iceland Research Fund [2014–2016], Landspitali University Hospital ... |
author2 |
Matvæla- og næringarfræðideild (HÍ) Faculty of Food Science and Nutrition (UI) Félagsfræði-, mannfræði- og þjóðfræðideild (HÍ) Faculty of Sociology, Anthropology and Folkloristics (UI) Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) Félagsvísindasvið (HÍ) School of Social Sciences (UI) Háskóli Íslands University of Iceland |
format |
Article in Journal/Newspaper |
author |
Thorisdottir, Birna Gunnarsdottir, Ingibjorg Viðarsdóttir, Anna Guðrún Sigurðardóttir, Sigurveig Birgisdottir, Bryndis Eva Thorsdottir, Inga |
author_facet |
Thorisdottir, Birna Gunnarsdottir, Ingibjorg Viðarsdóttir, Anna Guðrún Sigurðardóttir, Sigurveig Birgisdottir, Bryndis Eva Thorsdottir, Inga |
author_sort |
Thorisdottir, Birna |
title |
Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort |
title_short |
Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort |
title_full |
Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort |
title_fullStr |
Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort |
title_full_unstemmed |
Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort |
title_sort |
infant feeding, vitamin d and ige sensitization to food allergens at 6 years in a longitudinal icelandic cohort |
publisher |
MDPI AG |
publishDate |
2019 |
url |
https://hdl.handle.net/20.500.11815/1681 https://doi.org/10.3390/nu11071690 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Nutrients;11(7) https://www.mdpi.com/2072-6643/11/7/1690/pdf Thorisdottir, B.; Gunnarsdottir, I.; Vidarsdottir, A.G.; Sigurdardottir, S.; Birgisdottir, B.E.; Thorsdottir, I. Infant Feeding, Vitamin D and IgE Sensitization to Food Allergens at 6 Years in a Longitudinal Icelandic Cohort. Nutrients 2019, 11, 1690. 2072-6643 https://hdl.handle.net/20.500.11815/1681 Nutrients doi:10.3390/nu11071690 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/20.500.11815/1681 https://doi.org/10.3390/nu11071690 |
container_title |
Nutrients |
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11 |
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7 |
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1690 |
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1766039744702054400 |