Comparison Of Long-Term Antipsychotic Use Data From Medical Records And National Prescription Register
Background and aims. Prescription registers are increasingly applied to study long-term use of psychiatric medications. Information on drugs used during hospital care is missing from the registers. The aim of the current study was to compare cumulative amount of antipsychotics estimated from medical...
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| Format: | Other/Unknown Material |
| Language: | English |
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Morressier
2017
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| Online Access: | https://openresearchlibrary.org/viewer/6bfd4677-d069-4cac-97f6-8f20f46e3572 https://openresearchlibrary.org/ext/api/media/6bfd4677-d069-4cac-97f6-8f20f46e3572/assets/external_content.pdf https://doi.org/10.26226/morressier.5c642bed9ae8fb00131cf986 |
| Summary: | Background and aims. Prescription registers are increasingly applied to study long-term use of psychiatric medications. Information on drugs used during hospital care is missing from the registers. The aim of the current study was to compare cumulative amount of antipsychotics estimated from medical records and prescription register and effect of psychiatric hospital care on these estimates.Methods. The sample was based on the Northern Finland Birth Cohort 1966 including 54 individuals with psychoses. The data on defined daily dose years (DDDy) of antipsychotics was calculated for years 1998-2009 independently from medical records and nationwide prescription register. Sample was divided to two groups based on psychiatric inpatient care during follow-up (100 or more days vs. others).Results. In the prescription database median (maximum) DDDy was 5.1 (37.7) and in medical records 6.2 (329.0). The median DDDy among those who had at least 100 days psychiatric treatment days during the follow-up (n=21) was 8.8 in prescription register and 15.0 in medical records. Corresponding figures for others (n=33) were 3.6 and 2.0. The Spearmanu2019s rank correlation for the two DDDy variables was 0.77 for those who had been hospitalized at least 100 days and 0.86 for others. Conclusions. This was the first study comparing prescription register and medical records regarding psychiatric medication use. Prescription register lack substantial amount of antipsychotics among those who have had long periods in psychiatric hospitals, whereas among those with less hospital days medical records lack information. Constructing accurate estimates of lifetime antipsychotics use require data both from medical records and prescription registers. |
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