Molecular diagnostics for the detection of Bokeloh bat lyssavirus in a bat from Bavaria, Germany

A brain sample of a Natterer's bat tested positive for rabies with classical virological techniques. Molecular techniques confirmed the presence of Bokeloh bat lyssavirus (BBLV) in Germany for the second time. Sequence analysis revealed a close genetic relationship to the initial German BBLV ca...

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Bibliographic Details
Published in:Virus Research
Main Authors: Freuling, Conrad Martin, Abendroth, Björn, Beer, Martin, Fischer, Melina, Hanke, Dennis, Hoffmann, Bernd, Höper, Dirk, Just, F., Mettenleiter, Thomas C., Schatz, Juliane, Müller, Thomas
Format: Article in Journal/Newspaper
Language:English
Published: 2013
Subjects:
Text
ddc:570
Bokeloh bat lyssavirus
Bat rabies
Lyssaviruses
Realtime PCR
Microarray
Myotis nattereri
Natterer's bat
Online Access:https://doi.org/10.1016/j.virusres.2013.07.021
https://www.openagrar.de/receive/openagrar_mods_00002495
https://www.openagrar.de/servlets/MCRFileNodeServlet/Document_derivate_00002468/SD2013274.pdf
http://www.sciencedirect.com/science/article/pii/S0168170213002633
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Summary:A brain sample of a Natterer's bat tested positive for rabies with classical virological techniques. Molecular techniques confirmed the presence of Bokeloh bat lyssavirus (BBLV) in Germany for the second time. Sequence analysis revealed a close genetic relationship to the initial German BBLV case. Using a TaqMan RT-PCR specific for BBLV viral RNA was detected in various other organs albeit with differences in the relative viral load.

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