Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans: Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptom...

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Bibliographic Details
Published in:Emerging Infectious Diseases
Main Authors: Hoffmann, Donata, Breithaupt, Angele, Teifke, Jens Peter, Globig, Anja, Harder, Timm C., Mettenleiter, Thomas C., Beer, Martin
Format: Article in Journal/Newspaper
Language:English
Published: 2008
Subjects:
Text
ddc:630
antibody
avian influenza
BIRDS
GERMANY
H5N1
highly pathogenic
highly pathogenic avian influenza
IMMUNITY
PATHOBIOLOGY
SUBTYPE H5N1
VIRUS
Cygnus cygnus
Online Access:https://doi.org/10.3201/eid1408.080078
https://www.openagrar.de/receive/fimport_mods_00000963
https://www.openagrar.de/servlets/MCRFileNodeServlet/Document_derivate_00001438/SD200843.pdf
http://wwwnc.cdc.gov/eid/article/14/8/08-0078_article.htm
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600380/
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Summary:Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity

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