Psammopemmins (A-C), novel brominated 4-hydroxyindole alkaloids from an Antarctic sponge, Psammopemma sp.

Two specimens of a marine sponge Psammopemma sp. collected from Prydz Bay, Antarctica, have been found to contain three new brominated 4-hydroxyindole alkaloids: psammopemmin A (4), -B (5) and -C (6). These novel secondary metabolites, which also incorporate a unique 2-bromopyrimidine moiety, have b...

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Bibliographic Details
Main Authors: Butler, Mark S., Capon, Robert J., Lu, C. C.
Format: Article in Journal/Newspaper
Language:English
Published: Csiro Publishing 1992
Subjects:
Online Access:https://oceanrep.geomar.de/id/eprint/40106/
https://oceanrep.geomar.de/id/eprint/40106/1/Butler.pdf
Description
Summary:Two specimens of a marine sponge Psammopemma sp. collected from Prydz Bay, Antarctica, have been found to contain three new brominated 4-hydroxyindole alkaloids: psammopemmin A (4), -B (5) and -C (6). These novel secondary metabolites, which also incorporate a unique 2-bromopyrimidine moiety, have been assigned structures on the basis of detailed spectroscopic analysis and derivatization.