Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties

Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups. © 2005...

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Bibliographic Details
Main Authors: Barbayianni, E., Fotakopoulou, I., Schmidt, M., Constantinou-Kokotou, V., Bornscheuer, U.T., Kokotos, G.
Format: Article in Journal/Newspaper
Language:English
Published: 2005
Subjects:
Antarc*
Antarctica
Online Access:https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3067916
Description
Summary:Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups. © 2005 American Chemical Society.

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