Development and validation of methods of quantitative determination of the new antidiabetic drug in the blood plasma of rats by high performance liquid chromatography with mass spectrometric detection

We developed a method of quantification of the new antidiabetic drug 3-(1h-benzimidazole-2-yl)-1,2,2-trimethyl-cyclopentane-carbonic acid (c7070) in the blood plasma of rats by high-performance liquid chromatography with mass-spectrometric detection

Bibliographic Details
Published in:RESEARCH RESULT Pharmacology and Clinical Pharmacology
Main Authors: Buzov, A. A., Kulikov, A. L., Avtina, T. V., Pokrovskii, M. V., Osipova, O. A.
Format: Article in Journal/Newspaper
Language:English
Published: 2016
Subjects:
medicine
pharmacology
antidiabetic agent
the blood plasma of rats
high-performance liquid chromatography
mass spectrometric detection
validation
Carbonic acid
Online Access:https://openrepository.ru/article?id=457334
Description
Summary:We developed a method of quantification of the new antidiabetic drug 3-(1h-benzimidazole-2-yl)-1,2,2-trimethyl-cyclopentane-carbonic acid (c7070) in the blood plasma of rats by high-performance liquid chromatography with mass-spectrometric detection

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