DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin

Double stranded DNA was cleaved oxidatively by incubation with oxygenated myoglobin, and Lys96Cys sperm whale myoglobin in its stable ferric form functioned as an artificial nuclease under air by formation of an oxygenated species, owing to electron transfer from the SH group of the introduced cyste...

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Main Authors: Deshpande, Megha Subhash, Junedi, Sendy, Prakash, Halan, Nagao, Satoshi, Yamanaka, Masaru, Hirota, Shun
Format: Article in Journal/Newspaper
Language:English
Published: The Royal Society of Chemistry 2014
Subjects:
Online Access:http://hdl.handle.net/10061/10414
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spelling ftnarainstitute:oai:library.naist.jp:10061/10414 2023-05-15T18:26:36+02:00 DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin Deshpande, Megha Subhash Junedi, Sendy Prakash, Halan Nagao, Satoshi Yamanaka, Masaru Hirota, Shun 2014-10-10 application/pdf http://hdl.handle.net/10061/10414 en eng The Royal Society of Chemistry 10.1039/C4CC06617K 1359-7345 http://hdl.handle.net/10061/10414 AA11071130 Chemical Communications 50 95 15034 15036 73293425 73298382 73293409 c The Royal Society of Chemistry 2014 出版社許諾条件により、本文は2015年10月10日以降公開 Journal Article 2014 ftnarainstitute 2022-05-15T05:20:51Z Double stranded DNA was cleaved oxidatively by incubation with oxygenated myoglobin, and Lys96Cys sperm whale myoglobin in its stable ferric form functioned as an artificial nuclease under air by formation of an oxygenated species, owing to electron transfer from the SH group of the introduced cysteine to the heme. Article in Journal/Newspaper Sperm whale Nara Institute of Science and Technology: naistar (NAIST Academic Repository)
institution Open Polar
collection Nara Institute of Science and Technology: naistar (NAIST Academic Repository)
op_collection_id ftnarainstitute
language English
description Double stranded DNA was cleaved oxidatively by incubation with oxygenated myoglobin, and Lys96Cys sperm whale myoglobin in its stable ferric form functioned as an artificial nuclease under air by formation of an oxygenated species, owing to electron transfer from the SH group of the introduced cysteine to the heme.
format Article in Journal/Newspaper
author Deshpande, Megha Subhash
Junedi, Sendy
Prakash, Halan
Nagao, Satoshi
Yamanaka, Masaru
Hirota, Shun
spellingShingle Deshpande, Megha Subhash
Junedi, Sendy
Prakash, Halan
Nagao, Satoshi
Yamanaka, Masaru
Hirota, Shun
DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
author_facet Deshpande, Megha Subhash
Junedi, Sendy
Prakash, Halan
Nagao, Satoshi
Yamanaka, Masaru
Hirota, Shun
author_sort Deshpande, Megha Subhash
title DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
title_short DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
title_full DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
title_fullStr DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
title_full_unstemmed DNA cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
title_sort dna cleavage by oxymyoglobin and cysteine-introduced metmyoglobin
publisher The Royal Society of Chemistry
publishDate 2014
url http://hdl.handle.net/10061/10414
genre Sperm whale
genre_facet Sperm whale
op_relation 10.1039/C4CC06617K
1359-7345
http://hdl.handle.net/10061/10414
AA11071130
Chemical Communications
50
95
15034
15036
73293425
73298382
73293409
op_rights c The Royal Society of Chemistry 2014
出版社許諾条件により、本文は2015年10月10日以降公開
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