Re cent Desymmetrization Reactions By CALB

Enzyme reactions are among the most environmentally friendly and important asymmetric reactions for organic synthesis. Candida Antarctica lipase B (CALB) is one of the most extensively utilized enzymes for various asymmetric reactions. It catalyzes a variety of asymmetric reactions, such as hydrolys...

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Bibliographic Details
Published in:International Journal of Applied Chemistry
Main Author: NIWAYAMA Satomi
Format: Article in Journal/Newspaper
Language:English
Published: Seventh Sense Research Group 2020
Subjects:
enzyme
desymmetrization
CALB
building block
organic synthesis
574
Antarc*
Antarctica
Online Access:https://muroran-it.repo.nii.ac.jp/?action=repository_uri&item_id=10478
http://hdl.handle.net/10258/00010417
https://muroran-it.repo.nii.ac.jp/?action=repository_action_common_download&item_id=10478&item_no=1&attribute_id=24&file_no=1
Description
Summary:Enzyme reactions are among the most environmentally friendly and important asymmetric reactions for organic synthesis. Candida Antarctica lipase B (CALB) is one of the most extensively utilized enzymes for various asymmetric reactions. It catalyzes a variety of asymmetric reactions, such as hydrolysis, esterification, and amidation. However, as the studies of desymmetrization reactions of symmetric compounds catalyzed by CALB is rather limited, this commentary focuses on some recent examples of desymmetrization reactions mediated by CALB.

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