Perineural 5% dextrose versus corticosteroid injection in non-surgical carpal tunnel syndrom treatment = Perineuralis 5%-os dextróz kontra kortikoszteroid-injekció a carpalis alagút szindróma nem sebészi kezelésében

• Published in: Ideggyógyászati szemle
• Main Authors: Ocek, Ozge, Guner, Derya
• Format: Article in Journal/Newspaper
• Language: English
• Published: LifeTime Media Kft 2024
• Subjects: RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan; neurológia; pszichiátria; DML
• Online Access: https://real.mtak.hu/193692/; https://real.mtak.hu/193692/1/Ideggyogy_Sz_2024_77_121-129.pdf; https://doi.org/10.18071/isz.77.0121

Background and purpose – We aimed to investigate the difference of clinical and electrophysiological improvement between perineural corticosteroid injection therapy (PCIT) and perineural 5% dextrose injection therapy (5%PDIT) in carpal tunnel syndrome (CTS). Methods – Total of 92 wrists that were di- agnosed as mild-to-moderate idiopathic CTS and completed their follow-up were included in our study. The severity of pain, symptom severity and functional status were asses- sed by visual analog scale (VAS) and the Boston Carpal Tunnel Syndrome Question- naire (BCTQ) scores for treatment effective- ness. Randomized wrists were administered PCIT or 5%PDIT accompanied by ultrasound guidance. VAS, BCTQ scores and the electro- physiological study repeated before and after treatment at the 1st and 6th months after perineural injection therapies (PITs) were recorded. Results – Compared with baseline data, within groups there was significant improve- ment in VAS, BCTQ severity and function scores at 1st and 6th months follow-up (all p < 0.001). Considerable advance were de- tected in the median sensory nerve conduc- tion velocity (SNCV) when pretreatment val- ues were compared with posttreatment first month in both groups (p = 0.01; p < 0.001, respectively). No significant change occurred in median distal motor latency (DML) values between the 1st and 6th months in the groups (p = 0.095; p = 0.113, respectively). No significant difference was observed bet- ween 5%PDIT and PCIT groups. Conclusion – Clinical and electrophysiologic improvement in CTS began from 1st month after PCIT and 5%PDIT. At the 6th month fol- low-up of the patients, 5%PDIT and PCIT had similar therapeutic effects. As a result, we can consider the replacement of PCIT with 5%PDIT in mild-to-moderate CTS patients especially in those who are hesitant because of the corticosteroid’s adverse effects. | Háttér és cél – Tanulmányunk célja az volt, hogy megvizsgáljuk a klinikai és az elektro- fiziológiai javulás közötti különbségeket perineuralis ...