A Review: Meridianins and Meridianins Derivatives
Meridianins are a family of indole alkaloids derived from Antarctic tunicates with extensive pharmacological activities. A series of meridianin derivatives had been synthesized by drug researchers. This article reviews the extraction and purification methods, biological activities and pharmacologica...
| Published in: | Molecules |
|---|---|
| Main Author: | |
| Format: | Text |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2022
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| Subjects: | |
| Online Access: | https://doi.org/10.3390/molecules27248714 |
| _version_ | 1821668155771060224 |
|---|---|
| author | Linxia Xiao |
| author_facet | Linxia Xiao |
| author_sort | Linxia Xiao |
| collection | MDPI Open Access Publishing |
| container_issue | 24 |
| container_start_page | 8714 |
| container_title | Molecules |
| container_volume | 27 |
| description | Meridianins are a family of indole alkaloids derived from Antarctic tunicates with extensive pharmacological activities. A series of meridianin derivatives had been synthesized by drug researchers. This article reviews the extraction and purification methods, biological activities and pharmacological applications, pharmacokinetic characters and chemical synthesis of meridianins and their derivatives. And prospects on discovering new bioactivities of meridianins and optimizing their structure for the improvement of the ADMET properties are provided. |
| format | Text |
| genre | Antarc* Antarctic |
| genre_facet | Antarc* Antarctic |
| geographic | Antarctic |
| geographic_facet | Antarctic |
| id | ftmdpi:oai:mdpi.com:/1420-3049/27/24/8714/ |
| institution | Open Polar |
| language | English |
| op_collection_id | ftmdpi |
| op_coverage | agris |
| op_doi | https://doi.org/10.3390/molecules27248714 |
| op_relation | https://dx.doi.org/10.3390/molecules27248714 |
| op_rights | https://creativecommons.org/licenses/by/4.0/ |
| op_source | Molecules; Volume 27; Issue 24; Pages: 8714 |
| publishDate | 2022 |
| publisher | Multidisciplinary Digital Publishing Institute |
| record_format | openpolar |
| spelling | ftmdpi:oai:mdpi.com:/1420-3049/27/24/8714/ 2025-01-16T19:13:11+00:00 A Review: Meridianins and Meridianins Derivatives Linxia Xiao agris 2022-12-09 application/pdf https://doi.org/10.3390/molecules27248714 EN eng Multidisciplinary Digital Publishing Institute https://dx.doi.org/10.3390/molecules27248714 https://creativecommons.org/licenses/by/4.0/ Molecules; Volume 27; Issue 24; Pages: 8714 meridianins indole alkaloids biological activities pharmacological applications pharmacokinetic characters chemical synthesis prospects Text 2022 ftmdpi https://doi.org/10.3390/molecules27248714 2023-08-01T07:43:18Z Meridianins are a family of indole alkaloids derived from Antarctic tunicates with extensive pharmacological activities. A series of meridianin derivatives had been synthesized by drug researchers. This article reviews the extraction and purification methods, biological activities and pharmacological applications, pharmacokinetic characters and chemical synthesis of meridianins and their derivatives. And prospects on discovering new bioactivities of meridianins and optimizing their structure for the improvement of the ADMET properties are provided. Text Antarc* Antarctic MDPI Open Access Publishing Antarctic Molecules 27 24 8714 |
| spellingShingle | meridianins indole alkaloids biological activities pharmacological applications pharmacokinetic characters chemical synthesis prospects Linxia Xiao A Review: Meridianins and Meridianins Derivatives |
| title | A Review: Meridianins and Meridianins Derivatives |
| title_full | A Review: Meridianins and Meridianins Derivatives |
| title_fullStr | A Review: Meridianins and Meridianins Derivatives |
| title_full_unstemmed | A Review: Meridianins and Meridianins Derivatives |
| title_short | A Review: Meridianins and Meridianins Derivatives |
| title_sort | review: meridianins and meridianins derivatives |
| topic | meridianins indole alkaloids biological activities pharmacological applications pharmacokinetic characters chemical synthesis prospects |
| topic_facet | meridianins indole alkaloids biological activities pharmacological applications pharmacokinetic characters chemical synthesis prospects |
| url | https://doi.org/10.3390/molecules27248714 |