The Australian dingo is an early offshoot of modern breed dogs.

Dogs are uniquely associated with human dispersal and bring transformational insight into the domestication process. Dingoes represent an intriguing case within canine evolution being geographically isolated for thousands of years. Here, we present a high-quality de novo assembly of a pure dingo (Ca...

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Bibliographic Details
Main Authors: Matt A Field, Sonu Yadav, Olga Dudchenko, Meera Esvaran, Benjamin D Rosen, Ksenia Skvortsova, Richard J Edwards, Jens Keilwagen, Blake J Cochran, Bikash Manandhar, Sonia Bustamante, Jacob Agerbo Rasmussen, Richard G Melvin, Barry Chernoff, Arina Omer, Zane Colaric, Eva KF Chan, Andre E Minoche, Timothy PL Smith, M Thomas P Gilbert, Ozren Bogdanovic, Robert A Zammit, Torsten Thomas, Erez L Aiden, John Ballard
Format: Other Non-Article Part of Journal/Newspaper
Language:unknown
Published: 2022
Subjects:
Uncategorized
Animals
Australia
Breeding
Canidae
Dogs
Phylogeny
Wolves
Dingos
Greenland
Online Access:https://doi.org/10.26181/19719670.v1
https://figshare.com/articles/journal_contribution/The_Australian_dingo_is_an_early_offshoot_of_modern_breed_dogs_/19719670
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Summary:Dogs are uniquely associated with human dispersal and bring transformational insight into the domestication process. Dingoes represent an intriguing case within canine evolution being geographically isolated for thousands of years. Here, we present a high-quality de novo assembly of a pure dingo (CanFam_DDS). We identified large chromosomal differences relative to the current dog reference (CanFam3.1) and confirmed no expanded pancreatic amylase gene as found in breed dogs. Phylogenetic analyses using variant pairwise matrices show that the dingo is distinct from five breed dogs with 100% bootstrap support when using Greenland wolf as the outgroup. Functionally, we observe differences in methylation patterns between the dingo and German shepherd dog genomes and differences in serum biochemistry and microbiome makeup. Our results suggest that distinct demographic and environmental conditions have shaped the dingo genome. In contrast, artificial human selection has likely shaped the genomes of domestic breed dogs after divergence from the dingo.

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