| Summary: | Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open The purpose of this study was to estimate the relative and independent effect of tobacco smoking and serum cholesterol levels on arterial blood flow to the lower extremities in middel aged men without clinical symptoms of arterial disease. Ninety two men 40 to 60 years of age participated in the study. Forty eight were non-smokers (38 with serum cholesterol <220 mg/dl and ten with cholesterol >270 mg/dl). Forty four were smokers (30 had serum cholesterol <220 mg/dl and 14 had cholesterol >270 mg/dl). The anckle-brachial blood pressure index was calculated as well as a Doppler recording of blood flow velocity in both femoral arteries before and after a light exercise. The results show a lower anckle/brachial index and increased blood flow velocity in the femoral arteries of smokers as compared to non-smokers. Tobacco smoking was found to have a greater effect than elevated serum cholesterol on the blood flow parameters in this study. The effect of smoking and elevated serum cholesterol is additive (p<0.0001). This is more evident following a light exercise. Smokers had a higher resting heart rate and blood pressure was higher at both rest and exercise as compared to non-smokers (p<0.05). This may reflect a lower exercise tolerance in smokers. Non-smokers with lower serum cholesterol tended to have a lower resting heart rate and blood pressure. This may reflect a healthier cardiovascular system. Tilgangur rannsóknarinnar var að meta óháð áhrif reykinga og kólesteróls á slagæðablóðflæði til ganglima hjá miðaldra karlmönnum sem töldust án einkenna slagæðasjúkdóms. Níutíu og tveir karlmenn án einkenna um slagæðasjúkdóm, á aldrinum 40-60 ára, mættu til rannsóknarinnar. Fjörutíu og átta þeirra reyktu ekki tóbak (38 höfðu kólesterólgildi undir 220 mg/dl og 10 yfir 270 mg/dl) og 44 voru reykingamenn (30 höfðu kólesterólgildi undir 220 mg/dl og 14 yfir 270 mg/dl). Reiknað var hlutfall blóðþrýstings, sem ...
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