The Scandinavian Sarcoma Group Central Register: 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma.

• Published in: Acta Orthopaedica
• Main Authors: Trovik, Clement, Bauer, Henrik C F, Styring, Emelie, Sundby Hall, Kirsten, Vult Von Steyern, Fredrik, Eriksson, Sigvard, Johansson, Ingela, Sampo, Mika, Laitinen, Minna, Kalén, Anders, Jónsson, Halldór, Jebsen, Nina, Eriksson, Mikael, Tukiainen, Erkki, Wall, Najme, Zaikova, Olga, Sigurðsson, Helgi, Lehtinen, Tuula, Bjerkehagen, Bodil, Skorpil, Mikael, Egil Eide, Geir, Johansson, Elisabeth, Alvegard, Thor A
• Other Authors: 1 Haukeland Hosp, Dept Musculoskeletal Tumor Serv Oncol, Bergen, Norway Show the Organization-Enhanced name(s) 2 Karolinska Hosp, Dept Orthoped, Oncol Serv, Stockholm, Sweden Show the Organization-Enhanced name(s) 3 Lund Univ, Skane Univ Hosp, Dept Orthoped, Lund, Sweden Show the Organization-Enhanced name(s) 4 Oslo Univ Hosp, Norwegian Radium Hosp, Dept Oncol, Oslo, Norway Show the Organization-Enhanced name(s) 5 Sahlgrenska Hosp, Dept Orthoped, Gothenburg, Sweden Show the Organization-Enhanced name(s) 6 Norrland Univ Hosp, Dept Orthoped, Umea, Sweden Show the Organization-Enhanced name(s) 7 Helsinki Univ Hosp, Dept Oncol, Helsinki, Finland 8 Tampere Univ Hosp, Dept Orthoped, Tammerfors, Finland Show the Organization-Enhanced name(s) 9 Linkoping Univ Hosp, Dept Orthoped, Linkoping, Sweden 10 Landspitalin, Dept Orthoped, Reykjavik, Iceland Show the Organization-Enhanced name(s) 11 Lund Univ Hosp, Dept Oncol, Lund, Sweden Show the Organization-Enhanced name(s) 12 Helsinki Univ Hosp, Dept Plast Surg, Helsinki, Finland Show the Organization-Enhanced name(s) 13 Linkoping Univ Hosp, Dept Oncol, Linkoping, Sweden Show the Organization-Enhanced name(s) 14 Oslo Univ Hosp, Norwegian Radium Hosp, Dept Orthoped, Oslo, Norway 15 Landspitalin, Dept Oncol, Reykjavik, Iceland 16 Tampere Univ Hosp, Dept Oncol, Tammerfors, Finland Show the Organization-Enhanced name(s) 17 Oslo Univ Hosp, Norwegian Radium Hosp, Dept Pathol, Oslo, Norway Show the Organization-Enhanced name(s) 18 Akad Sjukhuset, Dept Radiol, Stockholm, Sweden Show the Organization-Enhanced name(s) 19 Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden Show the Organization-Enhanced name(s) 20 Haukeland Hosp, Dept Ctr Clin Res, Bergen, Norway Show the Organization-Enhanced name(s) 21 Univ Bergen, Dept Dept Global Publ Hlth & Primary Care, Bergen, Norway Show the Organization-Enhanced name(s) 22 Lund Univ Hosp, Dept Canc Epidemiol, Lund, Sweden.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Taylor & Francis 2017
• Subjects: Krabbamein; Stoðvefur; MAO12; ORT12; Sarcoma; Scandinavian and Nordic Countries; Norway; Iceland
• Online Access: http://hdl.handle.net/2336/620218; https://doi.org/10.1080/17453674.2017.1293441

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files Purpose - We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background - Based on incidence rates from the literature, 8,150 (7,000-9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results - 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation - The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers. National Advisory Unit on sarcomas in Norway Swedish Cancer Society