Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and...
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/4580 2023-05-15T16:49:08+02:00 Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study Jonasson, F Damji, K F Arnarsson, A Sverrisson, T Wang, L Sasaki, H Sasaki, K 2003-08-01 YES http://hdl.handle.net/2336/4580 https://doi.org/10.1038/sj.eye.6700374 en eng Nature Publishing Group http://www.nature.com/eye/journal/v17/n6/full/6700374a.html Eye 2003, 17(6):747-53 0950-222X 12928689 doi:10.1038/sj.eye.6700374 OPH12 http://hdl.handle.net/2336/4580 Eye (London, England) Age Distribution Aged Exfoliation Syndrome Female Glaucoma Open-Angle Humans Iceland/epidemiology Middle Aged Prevalence Research Support Non-U.S. Gov't Severity of Illness Index Sex Distribution Visual Acuity Article 2003 ftlandspitaliuni https://doi.org/10.1038/sj.eye.6700374 2022-05-29T08:20:53Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories:Category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5th percentile (>0.7), focal glaucomatous disc change, C/D asymmetry of 97.5th percentile difference between eyes (>0.2) as well as glaucomatous visual field defect (GVFD).Category 2: 99.5th percentile of VCDR (>0.8) and 99.5% percentile difference between eyes (>/=0.3), without a GVFD.Category 3: VA<3/60 and IOP>99.5th percentile or VA <3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR>99.5th percentile (>0.8), focal glaucomatous disc change, C/D asymmetry of 99.5th percentile (> or =0.3), GVFD only, IOP> or =23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0%) had PEX. The minimum prevalence of OAG was 4.0% (42/1045) (95% CI 2.8-5.2) for those 50 years and older and 10.3% (95% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR=1.10/year, 95% CI 1.07-1.13, P=0.000) and the same applies for the prevalence of PEX, OR=1.10 (95% CI 1.07-1.12, P=0.000). CONCLUSION: There is a 10% annual increase for both OAG and PEX in persons 50 years and older. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Eye 17 6 747 753 |
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Hirsla - Landspítali University Hospital research archive |
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ftlandspitaliuni |
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English |
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Age Distribution Aged Exfoliation Syndrome Female Glaucoma Open-Angle Humans Iceland/epidemiology Middle Aged Prevalence Research Support Non-U.S. Gov't Severity of Illness Index Sex Distribution Visual Acuity |
spellingShingle |
Age Distribution Aged Exfoliation Syndrome Female Glaucoma Open-Angle Humans Iceland/epidemiology Middle Aged Prevalence Research Support Non-U.S. Gov't Severity of Illness Index Sex Distribution Visual Acuity Jonasson, F Damji, K F Arnarsson, A Sverrisson, T Wang, L Sasaki, H Sasaki, K Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study |
topic_facet |
Age Distribution Aged Exfoliation Syndrome Female Glaucoma Open-Angle Humans Iceland/epidemiology Middle Aged Prevalence Research Support Non-U.S. Gov't Severity of Illness Index Sex Distribution Visual Acuity |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories:Category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5th percentile (>0.7), focal glaucomatous disc change, C/D asymmetry of 97.5th percentile difference between eyes (>0.2) as well as glaucomatous visual field defect (GVFD).Category 2: 99.5th percentile of VCDR (>0.8) and 99.5% percentile difference between eyes (>/=0.3), without a GVFD.Category 3: VA<3/60 and IOP>99.5th percentile or VA <3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR>99.5th percentile (>0.8), focal glaucomatous disc change, C/D asymmetry of 99.5th percentile (> or =0.3), GVFD only, IOP> or =23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0%) had PEX. The minimum prevalence of OAG was 4.0% (42/1045) (95% CI 2.8-5.2) for those 50 years and older and 10.3% (95% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR=1.10/year, 95% CI 1.07-1.13, P=0.000) and the same applies for the prevalence of PEX, OR=1.10 (95% CI 1.07-1.12, P=0.000). CONCLUSION: There is a 10% annual increase for both OAG and PEX in persons 50 years and older. |
format |
Article in Journal/Newspaper |
author |
Jonasson, F Damji, K F Arnarsson, A Sverrisson, T Wang, L Sasaki, H Sasaki, K |
author_facet |
Jonasson, F Damji, K F Arnarsson, A Sverrisson, T Wang, L Sasaki, H Sasaki, K |
author_sort |
Jonasson, F |
title |
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study |
title_short |
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study |
title_full |
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study |
title_fullStr |
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study |
title_full_unstemmed |
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study |
title_sort |
prevalence of open-angle glaucoma in iceland: reykjavik eye study |
publisher |
Nature Publishing Group |
publishDate |
2003 |
url |
http://hdl.handle.net/2336/4580 https://doi.org/10.1038/sj.eye.6700374 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.nature.com/eye/journal/v17/n6/full/6700374a.html Eye 2003, 17(6):747-53 0950-222X 12928689 doi:10.1038/sj.eye.6700374 OPH12 http://hdl.handle.net/2336/4580 Eye (London, England) |
op_doi |
https://doi.org/10.1038/sj.eye.6700374 |
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Eye |
container_volume |
17 |
container_issue |
6 |
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747 |
op_container_end_page |
753 |
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