Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and...

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Bibliographic Details
Published in:Eye
Main Authors: Jonasson, F, Damji, K F, Arnarsson, A, Sverrisson, T, Wang, L, Sasaki, H, Sasaki, K
Format: Article in Journal/Newspaper
Language:English
Published: Nature Publishing Group 2003
Subjects:
Age Distribution
Aged
Exfoliation Syndrome
Female
Glaucoma
Open-Angle
Humans
Iceland/epidemiology
Middle Aged
Prevalence
Research Support
Non-U.S. Gov't
Severity of Illness Index
Sex Distribution
Visual Acuity
Iceland
Online Access:http://hdl.handle.net/2336/4580
https://doi.org/10.1038/sj.eye.6700374
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Summary:To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories:Category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5th percentile (>0.7), focal glaucomatous disc change, C/D asymmetry of 97.5th percentile difference between eyes (>0.2) as well as glaucomatous visual field defect (GVFD).Category 2: 99.5th percentile of VCDR (>0.8) and 99.5% percentile difference between eyes (>/=0.3), without a GVFD.Category 3: VA<3/60 and IOP>99.5th percentile or VA <3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR>99.5th percentile (>0.8), focal glaucomatous disc change, C/D asymmetry of 99.5th percentile (> or =0.3), GVFD only, IOP> or =23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0%) had PEX. The minimum prevalence of OAG was 4.0% (42/1045) (95% CI 2.8-5.2) for those 50 years and older and 10.3% (95% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR=1.10/year, 95% CI 1.07-1.13, P=0.000) and the same applies for the prevalence of PEX, OR=1.10 (95% CI 1.07-1.12, P=0.000). CONCLUSION: There is a 10% annual increase for both OAG and PEX in persons 50 years and older.

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