Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosa.

To access publisher's full text version of this article click on the hyperlink at the bottom of the page To assess retinal vessel oxygen saturation and retinal vessel diameter in retinitis pigmentosa. A retinal oximeter (Oxymap ehf., Reykjavik, Iceland) was used to measure retinal vessel oxygen...

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Bibliographic Details
Published in:Acta Ophthalmologica
Main Authors: Eysteinsson, Thor, Hardarson, Sveinn H, Bragason, David, Stefánsson, Einar
Other Authors: Univ Iceland, Reykjavik, Iceland, Univ Iceland, Landspitali Univ Hosp, Reykjavik, Iceland
Format: Article in Journal/Newspaper
Language:English
Published: Wiley-Blackwell 2014
Subjects:
Sjónhimna
Sykursýki
Sjónskerðing
Retinal Vessels
Oxygen/blood
Retinitis Pigmentosa
Diabetic Retinopathy
Pigmentation
Epithelium
Oximetry
Adult
Blood Pressure/physiology
Female
Humans
Intraocular Pressure/physiology
Male
Middle Aged
Retina/pathology
Retinal Artery/physiopathology*
Retinal Vein/physiopathology*
Retinitis Pigmentosa/physiopathology*
Tomography
Optical Coherence
Young Adult
Iceland
Online Access:http://hdl.handle.net/2336/325945
https://doi.org/10.1111/aos.12359
Description
Summary:To access publisher's full text version of this article click on the hyperlink at the bottom of the page To assess retinal vessel oxygen saturation and retinal vessel diameter in retinitis pigmentosa. A retinal oximeter (Oxymap ehf., Reykjavik, Iceland) was used to measure retinal vessel oxygen saturation and vessel diameter in ten patients with retinitis pigmentosa (RP) (mean age 49 years, range 23-71 years). Results were compared with age- and gender-matched healthy individuals. All patients had advanced stage of the disease with visual fields restricted to the macular region. Oxygen saturation in retinal venules was 58.0 ± 6.2% in patients with RP and 53.4 ± 4.8% in healthy subjects (p = 0.017). Oxygen saturation in retinal arterioles was not significantly different between groups (p = 0.65). The mean diameter of retinal arterioles was 8.9 ± 1.6 pixels in patients with RP and 11.4 ± 1.2 in healthy controls (p < 0.0001). The corresponding diameters for venules were 10.1 ± 1.2 (RP) and 15.3 ± 1.7 (healthy, p < 0.0001). Increased venous saturation and decreased retinal vessel diameter suggest decreased oxygen delivery from the retinal circulation in retinitis pigmentosa. This is probably secondary to tissue atrophy and reduced oxygen consumption.

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