Temporal trends in the incidence of kidney stone disease.

• Published in: Kidney International
• Main Authors: Edvardsson, Vidar O, Indridason, Olafur S, Haraldsson, Gudjon, Kjartansson, Olafur, Palsson, Runolfur
• Other Authors: Natl Univ Hosp Iceland, Div Nephrol, Landspitali, Childrens Med Ctr, IS-101 Reykjavik, Iceland, Natl Univ Hosp Iceland, Div Nephrol, Landspitali, Internal Med Serv, IS-101 Reykjavik, Iceland, Natl Univ Hosp Iceland, Div Radiol, Landspitali, Diagnost Med Serv, IS-101 Reykjavik, Iceland
• Format: Article in Journal/Newspaper
• Language: English
• Published: Nature Pub. Group 2013
• Subjects: Nýrnasteinar; Adolescent; Adult; Aged; 80 and over; Female; Humans; Iceland; Incidence; Kidney Calculi; Male; Middle Aged; Regression Analysis; Retrospective Studies; Young Adult
• Online Access: http://hdl.handle.net/2336/312793; https://doi.org/10.1038/ki.2012.320

To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Recent reports show an increased occurrence of kidney stone disease worldwide. To further evaluate and quantify this observation, we examined recent trends in the incidence of kidney stone disease in the adult population of Iceland over a 24-year period. Computerized databases of all major hospitals and medical imaging centers in Iceland were searched for International Classification of Diseases, radiologic and surgical procedure codes indicative of kidney stones in patients aged 18 years and older. The time trends in stone frequency of 5945 incident patients (63% men) were assessed by Poisson regression analysis. The majority of patients (90.5%) had symptomatic stone disease. The total incidence of kidney stones rose significantly from 108 per 100,000 in the first 5-year interval of the study to 138 per 100,000 in the last interval. The annual incidence of symptomatic stones did not increase significantly in either men or women. There was, however, a significant increase in the annual incidence of asymptomatic stones over time, from 7 to 24 per 100,000 for men and from 7 to 21 per 100,000 for women. The increase in the incidence of asymptomatic stones was only significant for women above 50 years of age and for men older than 40 years. Thus, we found a significant increase in the incidence of kidney stone disease resulting from increased detection of asymptomatic stones. This was largely due to a more frequent use of high-resolution imaging studies in older patients. Landspitali -The National University Hospital of Iceland Research Fund