Endothelial-rich microenvironment supports growth and branching morphogenesis of prostate epithelial cells.

To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Development of epithelial organs depends on interaction between the epithelium and the underlying mesenchyme including the vasculature. The aim of this study was to explore the morp...

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Bibliographic Details
Published in:The Prostate
Main Authors: Bergthorsson, Jon Thor, Magnusson, Magnus Karl, Gudjonsson, Thorarinn
Other Authors: Univ Iceland, Sch Hlth Sci, Biomed Ctr, Stem Cell Res Unit, Reykjavik, Iceland, Univ Iceland, Sch Hlth Sci, Dept Pharmacol & Toxicol, Reykjavik, Iceland, Landspitali Univ Hosp, Dept Lab Hematol, Reykjavik, Iceland
Format: Article in Journal/Newspaper
Language:English
Published: Wiley-Blackwell 2013
Subjects:
Frumurannsóknir
Blöðruhálskirtill
Cell Line
Epithelial Cells
Epithelial-Mesenchymal Transition
Flow Cytometry
Humans
Immunohistochemistry
Male
Morphogenesis
Organ Culture Techniques
Prostate
Iceland
Online Access:http://hdl.handle.net/2336/312637
https://doi.org/10.1002/pros.22634
Description
Summary:To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Development of epithelial organs depends on interaction between the epithelium and the underlying mesenchyme including the vasculature. The aim of this study was to explore the morphogenic effect of endothelial cells on prostate epithelial cell lines in 3D culture and to establish an in vitro model for prostate branching morphogenesis. Icelandic Centre for Research/100444042 Icelandic Cancer Society University of Iceland Research Fund Bergthora Magnusdottir and Jakob J. Bjarnasson Memory Fund

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