Oxygen saturation in branch retinal vein occlusion.

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. The aim of this study was to test whether oxygen saturation in retinal blood vessels is affected by branch retinal vein occlusion (BRVO). The spectrophotometric retinal oximeter is based o...

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Bibliographic Details
Published in:Acta Ophthalmologica
Main Authors: Hardarson, Sveinn Hakon, Stefánsson, Einar
Other Authors: Department of Ophthalmology, University of Iceland/ Landspítali - The National University Hospital of Iceland, Reykjavik, Iceland.
Format: Article in Journal/Newspaper
Language:English
Published: 2013
Subjects:
Adult
Aged
80 and over
Arterioles
Humans
Middle Aged
Oximetry
Oxygen
Oxygen Consumption
Regional Blood Flow
Retinal Artery
Retinal Vein
Retinal Vein Occlusion
Venules
Iceland
Online Access:http://hdl.handle.net/2336/299645
https://doi.org/10.1111/j.1755-3768.2011.02109.x
Description
Summary:To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. The aim of this study was to test whether oxygen saturation in retinal blood vessels is affected by branch retinal vein occlusion (BRVO). The spectrophotometric retinal oximeter is based on a fundus camera. It simultaneously captures images of the retina at 586 and 605 nm and calculates optical density (absorbance) of retinal vessels at both wavelengths. The ratio of the two optical densities is approximately linearly related to haemoglobin oxygen saturation. Relative oxygen saturation was measured in retinal blood vessels in 24 patients with BRVO. Friedman's test and Dunn's post test were used for statistical analyses. Results: Oxygen saturation in occluded venules ranged from 12% to 93%. The median oxygen saturation was 59% (range 12-93%, n = 22) in affected retinal venules, 63% (23-80%) in unaffected venules in the BRVO eye and 55% (39-80%) in venules in the fellow eye (p = 0.66). Corresponding values for arterioles were 101% (89-115%, n = 18), 95% (85-104%) (p < 0.05) and 98% (84-109%). Venular saturation in BRVO is highly variable between patients. Hypoxia is seen in some eyes but not in others. This may reflect variable severity of disease, degree of occlusion, recanalization, collateral circulation, tissue atrophy, arteriovenous diffusion or vitreal transport of oxygen. Icelandic Center for Research (Ranni's) Eimskip University Fund University of Iceland Research Fund Landspitali-University Hospital Research Fund Helga Jonsdottir and Sigurlidi Kristjansson Memorial Fund

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