Age-related macular degeneration in very old individuals with family history

To access Publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To study age-related macular degeneration (AMD) in old and very old individuals with family history of AMD to find the proportion of those with early and advanced AMD. DESIGN: Retr...

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Bibliographic Details
Published in:American Journal of Ophthalmology
Main Authors: Geirsdottir, Asbjorg, Stefansson, Einar, Jonasson, Fridbert, Helgadottir, Gudleif, Sigurdsson, Haraldur
Format: Article in Journal/Newspaper
Language:English
Published: Elsevier Science 2007
Subjects:
Aged
80 and over
Cross-Sectional Studies
Family Health
Female
Genetic Predisposition to Disease
Humans
Iceland
Macular Degeneration
Male
Retrospective Studies
Online Access:http://hdl.handle.net/2336/12474
https://doi.org/10.1016/j.ajo.2006.11.057
Description
Summary:To access Publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To study age-related macular degeneration (AMD) in old and very old individuals with family history of AMD to find the proportion of those with early and advanced AMD. DESIGN: Retrospective cross-sectional cohort study of individuals with family history of AMD. METHODS: Database of 897 AMD patients ages 75 to 102 years with family history of AMD was compiled. Color fundus photographs were graded in a masked fashion according to the International Classification of AMD. RESULTS: With increasing age, a gradually larger proportion of participants had advanced AMD; 54% (469 of 863) of all those 75 years and older had advanced AMD, 64% (258 of 406) of all those 85 years and older, 74% (37 of 50) of all those 95 years and older, and all (eight of eight) 100 years and older had advanced AMD. CONCLUSIONS: All the centenarians in the present study had advanced AMD.

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