| Summary: | Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open) Objective: This study is a part of EuroPrevall, an EU-funded European food allergy project. The aim was to evaluate the prevalence of food allergy in Icelandic infants during their first year of life. Material and methods: Infants (n=1,341) were followed prospectively from birth to 12 months of age. Questionnaires were obtained at birth and 12 months. Children with symptoms of possible food allergy were assessed with a skin-prick test (SPT) and specific IgE. Food allergy was confirmed with a double-blind placebo-controlled food challenge (DBPCFC). Results: Out of 170 symptomatic children 44 infants (3.27%) had either positive SPT (n=21; 1.57%) or specific IgE (n=40; 2.98%). Food allergy was confirmed in 25 (1.86%); egg allergy 1.42%, milk 0.52%, fish 0.22%, wheat 0.15%, peanuts 0.15%, and soy 0.07%. Atopic dermatitis was diagnosed in 7.90% (n=106) and according to questionnaires 8.80% had asthma (n=118). Positive family history was the strongest risk factor for asthma (OR=2.12; p<0.001) and atopic dermatitis (OR=1.90; p=0.004). Family history influenced the relationship between predisposing factors and allergy symptoms. Conclusion: Our results show lower prevalence of food allergy than previously reported in a study of Icelandic children at two years of age. The prevalence was also lower than reported in some other European countries and could be explained by different genetic and environmental factors.Key words: exem, infants, food allergy, prevalence, asthma, atopic dermatitis. Inngangur: Rannsóknin er hluti af alþjóðlegri fæðuofnæmisrannsókn, EuroPrevall. Markmiðið var að rannsaka algengi fæðuofnæmis hjá íslenskum börnum á fyrsta ári. Efniviður og aðferðir: Börnum (n=1341) var fylgt eftir frá fæðingu til eins árs aldurs. Spurningalistar voru lagðir fyrir við fæðingu og 12 mánaða aldur. Barn með einkenni fæðuofnæmis var skoðað af rannsóknarlækni, ofnæmishúðpróf gerð og sértækt IgE mælt. ...
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