Bacteraemia in children in Iceland 1994-2005

• Published in: Acta Paediatrica
• Main Authors: Arnason, Sigurdur, Thors, Valtyr Stefansson, Guðnason, Thorolfur, Kristinsson, Karl G, Haraldsson, Asgeir
• Format: Article in Journal/Newspaper
• Language: English
• Published: Taylor & Francis 2010
• Subjects: Child; Bacteremia; Sepsis; Streptococcus Pneumoniae; Neisseria meningitidis; Iceland
• Online Access: http://hdl.handle.net/2336/111684; https://doi.org/10.1111/j.1651-2227.2010.01841.x

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Aim: To investigate the aetiology of bacteraemia in children in Iceland, the antibiotic resistance and possible preventive measures. Methods: All positive bacterial blood cultures from children 0–18 years old isolated at Landspítali University Hospital Iceland from 1994 to 2005 were included in the study. Epidemiological and microbiological data were registered. The blood cultures were categorized according to likelihood of infection or contamination. Results: During the study period 1253 positive blood cultures were obtained from 974 children; 647 from boys and 606 from girls. Positive blood cultures were most common during the first year of life (594; 47.4%) with 252 of them from neonates. Coagulase negative staphylococci were most common (37%). Of probable or definite infections Streptococcus pneumoniae was the most common (19.3%) followed by Staphylococcus aureus (17.6%) and Neisseria meningitidis (13.5%). The most common pneumococcal serogroups were 23, 6, 7, 19 and 14. Commercially available vaccines contain up to 88% of all pneumococcal strains and 67% of all multi-resistant strains. N. meningitidis group C was not isolated after vaccinations were started in 2002. Conclusion: Our study provides important epidemiological data on bacterial bloodstream infections in children in Iceland. The results demonstrate the excellent efficacy of meningococcal group C vaccination.