RESULTS OF ETIOLOGIC DIAGNOSTICS OF TUBERCULOSIS IN THOSE WITH TB/HIV CO-INFECTION IN THE REPUBLIC OF KARELIA
The article presents the analysis of specific clinical and X-ray forms of tuberculosis and results of its etiologic diagnostics in 159 patients with TB/HIV co-infection in the Republic of Karelia from 2001 to 2016. In the Republic of Karelia, it was found out that cavities in lung tissue were less f...
Published in: | Tuberculosis and lung diseases |
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Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | Russian |
Published: |
Медицинские знания и технологии
2018
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Subjects: | |
Online Access: | https://www.tibl-journal.com/jour/article/view/1080 https://doi.org/10.21292/2075-1230-2018-96-1-18-23 |
Summary: | The article presents the analysis of specific clinical and X-ray forms of tuberculosis and results of its etiologic diagnostics in 159 patients with TB/HIV co-infection in the Republic of Karelia from 2001 to 2016. In the Republic of Karelia, it was found out that cavities in lung tissue were less frequent (38.5%) in those with TB/HIV co-infection, however, such patients had infectious forms more often (68.5%) versus pulmonary tuberculosis patients (data from Form no.33). It was defined that improvement of sputum collection would significantly enhance the frequency of tuberculous mycobacteria detection (at least by 20%) in those with pulmonary tuberculosis and HIV infection, which was very important for rapid diagnostics of the disease and prescription of adequate treatment, especially given the fact that nearly ½ (52.8%) of patients suffered from multiple drug resistance. Проведен анализ особенностей клинико-рентгенологических форм туберкулеза и результатов его этиологической диагностики у 159 больных коинфекцией ВИЧ-инфекция и туберкулез за период 2001-2016 гг. в Республике Карелия (РК). Установлено, что среди больных сочетанной инфекцией (ВИЧ-инфекция и легочный туберкулез) достоверно реже выявляются полости распада в легочной ткани (38,5%), однако достоверно чаще ‒ бактериовыделение (68,5%), чем среди больных легочным туберкулезом на территории РК (данные ф. 33). Определено, что улучшение организации сбора мокроты может существенно повысить (не менее чем на 20%) частоту выявления микобактерий туберкулеза (МБТ) у больных легочным туберкулезом и ВИЧ-инфекцией, что имеет важное значение в быстрой диагностике заболевания и назначении адекватной терапии, особенно учитывая, что среди больных сочетанной инфекцией ½ (52,8%) имели множественную лекарственную устойчивость МБТ. |
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