Influence of Ecological Factors on Formation of Viruses' Genetic Determinants and the Severity of Children's Clinical Course of Infections

The analysis of the epidemic process of manifestation and clinical features of measles in the last 200 years has been made and made clear the features of the formation of the genetic determinants of rubella virus at low and high temperatures of cultivation. Moreover epidemic dynamics of the process...

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Bibliographic Details
Published in:CHILDREN INFECTIONS
Main Authors: A. Dubov V., А. ДУБОВ В.
Format: Article in Journal/Newspaper
Language:Russian
Published: Association of Pediatricians and Infection Disease doctors, LLC "Diagnostics and Vaccines" 2016
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/219
https://doi.org/10.22627/2072-8107-2016-15-2-15-19
Description
Summary:The analysis of the epidemic process of manifestation and clinical features of measles in the last 200 years has been made and made clear the features of the formation of the genetic determinants of rubella virus at low and high temperatures of cultivation. Moreover epidemic dynamics of the process and the severity of the clinical course of measles in the pre—vaccine and vaccination periods in the middle latitudes of the globe, and in areas with extremely high and low temperatures was established. Проведен анализ проявления эпидемического процесса и особенностей клиники кори за последние 200 лет. Выявлены особенности формирования генетических детерминант вируса краснухи при низких и высоких температурах культивирования, установлена динамика эпидемического процесса и тяжести клинического течения кори в допрививочный и прививочный периоды в средних широтах Земного шара и в зонах с экстремально высокими и низкими температурами воздуха.