Deep metric learning with locality sensitive mining for self-correcting source separation of neural spiking signals

• Published in: IEEE Transactions on Cybernetics
• Main Authors: Farina, D, Clarke, A
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Institute of Electrical and Electronics Engineers 2023
• Subjects: DML
• Online Access: http://hdl.handle.net/10044/1/105325; https://doi.org/10.1109/TCYB.2023.3290825

Automated source separation algorithms have become a central tool in neuroengineering and neuroscience, where they are used to decompose neurophysiological signal into its constituent spiking sources. However, in noisy or highly multivariate recordings these decomposition techniques often make a large number of errors. Such mistakes degrade online human-machine interfacing methods and require costly post-hoc manual cleaning in the offline setting. In this paper we propose an automated error correction methodology using a deep metric learning (DML) framework, generating embedding spaces in which spiking events can be both identified and assigned to their respective sources. Furthermore, we investigate the relative ability of different DML techniques to preserve the intra-class semantic structure needed to identify incorrect class labels in neurophysiological time series. Motivated by this analysis, we propose locality sensitive mining, an easily implemented sampling-based augmentation to typical DML losses which substantially improves the local semantic structure of the embedding space. We demonstrate the utility of this method to generate embedding spaces which can be used to automatically identify incorrectly-labelled spiking events with high accuracy