COMPARISON OF PROPOFOL WITH ENFLURANE DURING HYPOTENSIVE ANAESTHESIA FOR MIDDLE EAR SURGERY

Forty patients undergoing middle ear surgery were allocated randomly to receive propofol induction and maintenance, or thiopentone induction and enflurane maintenance for anaesthesia. Both groups also received fentanyl, alcuronium, nitrous oxide and oxygen. If this did not reduce systolic arterial p...

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Bibliographic Details
Published in:British Journal of Anaesthesia
Main Authors: BEMBRIDGE, J. L., MOSS, E., GRUMMITT, R. M., NOBLE, J.
Format: Text
Language:English
Published: Oxford University Press 1993
Subjects:
Short Communication
GTN-P
Online Access:http://bja.oxfordjournals.org/cgi/content/short/71/6/895
https://doi.org/10.1093/bja/71.6.895
Description
Summary:Forty patients undergoing middle ear surgery were allocated randomly to receive propofol induction and maintenance, or thiopentone induction and enflurane maintenance for anaesthesia. Both groups also received fentanyl, alcuronium, nitrous oxide and oxygen. If this did not reduce systolic arterial pressure to 70 mm Hg, labetalol, glyceryl trinitrate (GTN), or both, was administered. Fifteen control patients had enflurane anaesthesia without hypotension. Pre- and postoperative psychometric tests were performed in all groups. The propofol group received significantly more labetalol ( P =0.0 14) and GTN ( P =0.004) than the enfiurane group. There was a greater increase in reaction times after operation in the study groups ( P <0.05) compared with controls. There was no difference between the propofol and enfiurane groups in control of arterial pressure, recovery from anaes thesia or psychometric testing. ( Br. J. Anaesth. 1993; 71: 895–897 )

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