NARWHAL, a primary analysis pipeline for NGS data

Summary: The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open source aligners and automated quality assessment. The entire pipeline can be run using only one simple samp...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Brouwer, R.W.W., van den Hout, M.C.G.N., Grosveld, F.G., van IJcken, W.F.J.
Format: Text
Language:English
Published: Oxford University Press 2011
Subjects:
Online Access:http://bioinformatics.oxfordjournals.org/cgi/content/short/btr613v1
https://doi.org/10.1093/bioinformatics/btr613
Description
Summary:Summary: The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open source aligners and automated quality assessment. The entire pipeline can be run using only one simple sample-sheet for diverse sequencing applications. Narwhal creates a sample oriented data structure and outperforms existing tools in speed. Availability: https://trac.nbic.nl/narwhal/ Supplementary information: Supplementary information is available at https://trac.nbic.nl/narwhal/ Contact: w.vanijcken@erasmusmc.nl