A double-edged sword – Metabolic complications of clozapine in a rural area

Dear Editor, Few studies examine the use of clozapine in rural and remote locations, or in First Nations Peoples. Despite efficacy in treatment resistant schizophrenia, the risk of haematological, cardiac and metabolic dysfunction can often be an impediment to clozapine initiation (Leucht et al., 20...

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Bibliographic Details
Published in:Schizophrenia Research
Main Authors: Bridson, Tahnee, Abeysundera, Hesitha, Arunachalam, Arulmathy, Lam, Anthea, McDermott, Brett, Mora, Linda, McGorry, Patrick, O'Donoghue, Brian
Format: Article in Journal/Newspaper
Language:English
Published: Elsevier 2021
Subjects:
Clinical sciences
Science & Technology
Life Sciences & Biomedicine
Psychiatry
Queensland
First Nations
Online Access:http://hdl.handle.net/10072/426217
https://doi.org/10.1016/j.schres.2020.12.043
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Summary:Dear Editor, Few studies examine the use of clozapine in rural and remote locations, or in First Nations Peoples. Despite efficacy in treatment resistant schizophrenia, the risk of haematological, cardiac and metabolic dysfunction can often be an impediment to clozapine initiation (Leucht et al., 2013). This presents an issue for those in rural locations with reduced access to psychiatric services (Hunter et al., 2011; Gynther et al., 2019). Our previous work has highlighted the difficulties in clozapine continuation, with over half ceasing within five years in Far North Queensland (FNQ) (Bridson et al., 2020). Here we address the metabolic complications associated with clozapine administration in this area. No Full Text

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