Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla

Long‐term cortisol infusion into freshwater (FW)‐adapted eels induced a significant increase in aquaporin‐1 (AQP1) mRNA expression within the esophageal epithelium of migratory “silver” eels, but not in nonmigratory, immature “yellow” eels. Cortisol treatment had no significant effect on the mRNA ab...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences
Main Authors: Martinez, Anne-Sophie, Wilson, Gillian, Phillips, Clair, Cutler, Christopher P., Hazon, Neil, Cramb, Gordon
Format: Text
Language:unknown
Published: Digital Commons@Georgia Southern 2005
Subjects:
Effect
Cortisol
Aquaporin expression
Esophagus
European eel
Anguilla anguilla
Biochemistry
Biophysics
and Structural Biology
Biology
Online Access:https://digitalcommons.georgiasouthern.edu/biology-facpubs/68
https://doi.org/10.1196/annals.1327.072
Description
Summary:Long‐term cortisol infusion into freshwater (FW)‐adapted eels induced a significant increase in aquaporin‐1 (AQP1) mRNA expression within the esophageal epithelium of migratory “silver” eels, but not in nonmigratory, immature “yellow” eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin‐1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

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