Embryotoxic and genotoxic effects of heavy metals and pesticides on early life stages of Pacific oyster (Crassostrea gigas)

[Departement_IRSTEA]Eaux [TR1_IRSTEA]BELCA International audience This study evaluated embryotoxicity and genotoxicity of two dissolved metals copper and cadmium (Cu and Cd) and two pesticides (metolachlor and irgarol) occurring in Arcachon Bay (SW France) in Pacific oyster (Crassostrea gigas) larva...

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Bibliographic Details
Published in:Marine Pollution Bulletin
Main Authors: Mai, Hong Ngoc, Cachot, J., Brune, J., Geffard, Olivier, Belles, A., Budzinski, H., Morin, Brice
Other Authors: Environnements et Paléoenvironnements OCéaniques (EPOC), Observatoire aquitain des sciences de l'univers (OASU), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1 (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Milieux aquatiques, écologie et pollutions (UR MALY), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)
Format: Article in Journal/Newspaper
Language:English
Published: HAL CCSD 2012
Subjects:
GENOTOXICITY
EMBRYOTOXICITY
HEAVY METALS
IRGAROL
METOLACHLOR
PACIFIC OYSTER
[SDE]Environmental Sciences
Crassostrea gigas
Pacific oyster
Online Access:https://hal.inrae.fr/hal-02598183
https://doi.org/10.1016/j.marpolbul.2012.10.009
Description
Summary:[Departement_IRSTEA]Eaux [TR1_IRSTEA]BELCA International audience This study evaluated embryotoxicity and genotoxicity of two dissolved metals copper and cadmium (Cu and Cd) and two pesticides (metolachlor and irgarol) occurring in Arcachon Bay (SW France) in Pacific oyster (Crassostrea gigas) larvae and investigated the relationship between those two endpoints. Embryotoxicity was measured by calculating the percentage of abnormal D-shaped larvae and genotoxicity was evaluated with DNA strand breaks using the comet assay. After 24 h exposure, significant increases of the percentage of abnormal D-larvae and the DNA strand breaks were observed from 0.1µg/L for Cu, 10 µg/L for Cd and 0.01 µg/L for both irgarol and metolachlor in comparison with the controls. A strong positive relationship between embryotoxicity and genotoxicity was recorded for Cu, Cd and metolachlor. The current study suggests that copper, irgarol and metolachlor can induce larval abnormalities and DNA damage in a population of exposed oysters at environmentally relevant concentrations.

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