Results of the clinical, echocardiographic and doppler program for aortic and pulmonary stenosis in Newfoundland and Landseer dogs in France: 756 dogs between 2010 and 2021

• Main Author: Fauveau, Constance
• Other Authors: École nationale vétérinaire d'Alfort (ENVA), Université Paris-Est Créteil Val-de-Marne - Faculté de médecine (UPEC Médecine), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Valérie Chetboul
• Format: Master Thesis
• Language: French
• Published: HAL CCSD 2022
• Subjects: Aortic stenosis; Pulmonary stenosis; Newfoundland dog; Landseer dog; Screening; Echocardiographic exam; Doppler exam; Médecine vétérinaire; Dépistage; Sténose aortique; Sténose pulmonaire; Échocardiographie; Doppler; Terre-Neuve (race canine); Landseer (race canine); France; [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health; Newfoundland; Terre-Neuve
• Online Access: https://dumas.ccsd.cnrs.fr/dumas-03978607; https://dumas.ccsd.cnrs.fr/dumas-03978607/document; https://dumas.ccsd.cnrs.fr/dumas-03978607/file/A-2022-082.pdf

Newfoundland and Landseer are predisposed to congenital arterial stenoses, particularly aortic stenosis (STAo). Tight arterial stenoses generally have a poor short-term prognosis, despite current surgical and medical treatment options. An arterial stenosis screening protocol was implemented by the Breed Club in 2010 to regulate the occurrence of these heart diseases. The purpose of the study performed was to analyze the different epidemiological information related to this screening between 2010 and 2021 and to study the subpopulation of dogs with arterial stenosis. A total of 756 dogs participated in the protocol thanks to 114 veterinarians, including 10 veterinarians specializing in cardiology (8.8%), distributed in 55 departments of metropolitan France. The median age of the dogs at the time of screening was 1.9 years (IQR interquartile range : 1.6-2.7) for a female:male ratio of 1.8, with no sexual predisposition to the occurrence of STAo. Of the 756 dogs in the protocol, the percentage of those affected was 1.12% (8 dogs) for STAo and 0.27% (2 dogs) for STAP. Only Newfoundland dogs had stenosis in this study no Landseer in the protocol was diagnosed with STAo or STAP. More than 90% of the dogs in the study required only a single examination to reach a diagnosis of stenosis, and the ability to detect murmurs, including low-grade murmurs, was similar between veterinarians (specialists and non-specialists). The SSBG murmur present in animals with STAo was also found in 5/691 (0.72%) dogs free of stenosis. The location of the aortic stenotic obstruction in STAo was predominantly subvalvular (75%) and no supravalvular stenosis was diagnosed. The median (interquartile range) maximum transaortic flow velocity (Vmax) in dogs free of any heart disease was 1.75 (1.59 to 1.93) m/s, whereas it was 3.06 (2.67 to 3.21) m/s for animals diagnosed as ""AS1."" No significant association between the presence of STAo and coat, inbreeding coefficient and diagnosis for hip and elbow dysplasia was found. In conclusion, the ...