The effect of phenolated "vaccines" against experimental T. cruzi infection in mice
"Vaccines" prepared from parasites of an avirulent cultivated Y strain of T. cruzi, suspended in phenolated 1/10.000 saline solution, with aluminum stearate, containing alive parasites, gave high degree of protection to mice against a posterior infection with virulent blood forms of the sa...
| Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Main Author: | |
| Format: | Article in Journal/Newspaper |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
1968
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| Online Access: | https://doi.org/10.1590/S0037-86821968000200003 https://doaj.org/article/ff153a0298e1453b9f5dfd64031aa632 |
| Summary: | "Vaccines" prepared from parasites of an avirulent cultivated Y strain of T. cruzi, suspended in phenolated 1/10.000 saline solution, with aluminum stearate, containing alive parasites, gave high degree of protection to mice against a posterior infection with virulent blood forms of the same parasites and strain. The degree of protection with 1/1000 and 1/10.000 phenol "vaccines", with no alive parasites, was very poor specially in the first group. The immunity seems to be related to the number of alive trypanosomes in the "vaccines". |
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