Incidencia de microorganismos en hemocultivos procesados en un hospital del estado Zulia y su resistencia a los agentes antimicrobianos
Abstract: Bloodstream infections cause significant morbidity and mortality worldwide. To determine in- cidence of the main microorganisms isolated from blood cultures and their antimicrobial resistance in a university hospital, 31,486 blood culture reports processed from January, 2008, to December,...
| Main Authors: | , , , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | English Spanish |
| Published: |
Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2015
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| Subjects: | |
| Online Access: | https://doaj.org/article/fd7f15c29c0b4886a6ba7df434d563e4 |
| Summary: | Abstract: Bloodstream infections cause significant morbidity and mortality worldwide. To determine in- cidence of the main microorganisms isolated from blood cultures and their antimicrobial resistance in a university hospital, 31,486 blood culture reports processed from January, 2008, to December, 2012, were reviewed. The percentage of positive blood cultures was 9.49%; the highest number was obtained in intensive care units (36.22%). 3,054 microorganisms were isolated: 67.62% Gram posi- tive, 25.51% Gram negative, 6.84% yeast and 0.03% strict anaerobes. The predominant organisms were coagulase-negative Staphylococcus, S. aureus, Candida spp., Klebsiella pneumoniae, Entero- coccus spp., Acinetobacter baumannii, Escherichia coli and Pseudomonas aeruginosa. Both, S. au- reus and the coagulase-negative species showed high resistance to oxacillin (72.0% and 88.9%, re- spectively) and sensitivity to vancomycin. A 26.4% of enterococci (E. faecium almost exclusively) were resistant to vancomycin. Acinetobacter baumannii and K. pneumoniae showed a high rate of resistance to the tested antibiotics. Overall, most of the microorganisms showed a progressive in- crease in antimicrobial resistance during the five years studied. It is necessary to review and adjust hospital policies for antibiotic use and strengthen control measures for the infected patient. Resumen: Las infecciones del torrente sanguíneo causan una importante morbi-mortalidad en todo el mundo. Para conocer la incidencia de los principales microorganismos aislados de hemocultivos y su resistencia antimicrobiana en un hospital universitario, se revisaron los informes de 31.486 he- mocultivos procesados desde enero de 2008 a diciembre de 2012. El porcentaje de hemocultivos positivos fue de 9,49%, el mayor número se obtuvo en las unidades de cuidados intensivos (36,22%). Se aislaron 3.054 microorganismos, 67,62% Gram positivos, 25,51% Gram negativos, 6,84% levaduras y 0,03% anaerobios estrictos. Los microorganismos predominantes fueron Staphylococcus coagulasa ... |
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