Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.

Abstract: INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic are...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Luís Fábio da Silva Batista, Vânia Lúcia Ribeiro da Matta, Thaise Yumie Tomokane, Acácio Duarte Pacheco, Fernando Tobias Silveira, Claudio Nazaretian Rossi, Mary Marcondes, Márcia Dalastra Laurenti
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2016
Subjects:
Canine leishmaniasis
Anti-Lutzomyia longipalpis saliva antibody
Transmissibility
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1590/0037-8682-0360-2015
https://doaj.org/article/f553f036aa3f4bd982c6e7338e57e28e
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Summary:Abstract: INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. RESULTS Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. CONCLUSIONS Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas.

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