Cancer Mortality Rates Increasing vs Cardiovascular Disease Mortality Decreasing in the World: Future Implications

• Published in: Mayo Clinic Proceedings: Innovations, Quality & Outcomes
• Main Authors: Karim ReFaey, MD, Shashwat Tripathi, BSA, Sanjeet S. Grewal, MD, Adip G. Bhargav, MD, David J. Quinones, Kaisorn L. Chaichana, MD, Samuel O. Antwi, PhD, Leslie T. Cooper, MD, Fredric B. Meyer, MD, Roxana S. Dronca, MD, Robert B. Diasio, MD, Alfredo Quinones-Hinojosa, MD
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2021
• Subjects: Medicine (General); R5-920; Antarc*; Antarctica
• Online Access: https://doi.org/10.1016/j.mayocpiqo.2021.05.005; https://doaj.org/article/f519c1eea8414299849367a25ddf8ef2

Objective: To highlight the current global trends in mortality for cardiovascular disease and cancer. Methods: The World Health Organization and the World Bank DataBank databases were used to analyze mortality rates for cancer and cardiovascular disease by calculating age-standardized mortality rates (ASRs) from 2000 to 2015 for high-income, upper-middle-income, and lower-middle-income countries. Data for cancer mortality and population for 43 countries representing 5 of the 7 continents (except Australia and Antarctica) were analyzed. Results: From 2000 to 2015, there was an increase in the ASR for cancer for both men and women irrespective of a country’s income status, representing an overall 7% increase in cancer ASR (Pearson r, +0.99; P<.00001). We report a higher ASR for cancer in high-income countries than in upper-middle-income and lower-middle-income countries specifically; high-income countries saw a 3% increase in cancer ASR vs +31% for upper-middle-income and +19% for lower-middle-income countries (P<.01). There has been a decrease in the ASR for cardiovascular disease for the 15 years analyzed (P<.00001). In addition, high-income countries had a higher ASR for cardiovascular disease than upper-middle-income countries during the 15-year period (P<.05). Conclusion: We suspect that because of early detection and targeted interventions, cardiovascular disease mortality rates have decreased during the past decade. On the basis of our results, cancer mortality rates continue to rise, with the projection of surpassing cardiovascular disease mortality rates in the near future.