Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?

ABSTRACT Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated t...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Ana Carolina Etrusco Zaroni Santos, Jaques Sztajnbok, Amaro Nunes Duarte-Neto, Amanda Freire Tamburini Sousa, Alessandra Geisler Daud Lopes, Anna Carlota Mott Barrientos
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2020
Subjects:
Gastrintestinal tuberculosis
Bleeding
Pediatric
Injectable antituberculous drugs
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946202062078
https://doaj.org/article/f3df9c6d311e45a5bfa7ac511bd4a619
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Summary:ABSTRACT Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs.

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