Nephrotic syndrome associated with toxoplasmosis: report of seven cases

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Julio Toporovski, Simone Romano, Suzana Hartmann, Wanda Benini, Pedro Paulo Chieffi
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 2012
• Subjects: Toxoplasma gondii; Nephrotic syndrome; Children; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/S0036-46652012000200001; https://doaj.org/article/f2d3c26de1ae4c36b840c00cc4581466

The concomitance of nephrotic syndrome and acute infection by Toxoplasma gondii is a rare occurrence in humans. In this paper seven cases of children, ranging from 11 months to 7 year-old, with concomitant nephrotic syndrome and asymptomatic acute T. gondii infection are reported. In one of those patients only the administration of anti-Toxoplasma therapy was enough to control the clinical and laboratory manifestations of the disease. In the other patients it was necessary to introduce corticosteroids or other immunosuppressant drugs. Three patients had complete clinical and laboratory improvement and the remaining showed only a partial response.