Nephrotic syndrome associated with toxoplasmosis: report of seven cases

The concomitance of nephrotic syndrome and acute infection by Toxoplasma gondii is a rare occurrence in humans. In this paper seven cases of children, ranging from 11 months to 7 year-old, with concomitant nephrotic syndrome and asymptomatic acute T. gondii infection are reported. In one of those pa...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Julio Toporovski, Simone Romano, Suzana Hartmann, Wanda Benini, Pedro Paulo Chieffi
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2012
Subjects:
Toxoplasma gondii
Nephrotic syndrome
Children
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/S0036-46652012000200001
https://doaj.org/article/f2d3c26de1ae4c36b840c00cc4581466
Description
Summary:The concomitance of nephrotic syndrome and acute infection by Toxoplasma gondii is a rare occurrence in humans. In this paper seven cases of children, ranging from 11 months to 7 year-old, with concomitant nephrotic syndrome and asymptomatic acute T. gondii infection are reported. In one of those patients only the administration of anti-Toxoplasma therapy was enough to control the clinical and laboratory manifestations of the disease. In the other patients it was necessary to introduce corticosteroids or other immunosuppressant drugs. Three patients had complete clinical and laboratory improvement and the remaining showed only a partial response.

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