Imported Plasmodium falciparum malaria in HIV-infected patients: a report of two cases

Abstract As HIV becomes a chronic infection, an increasing number of HIV-infected patients are travelling to malaria-endemic areas. Association of malaria with HIV/AIDS can be clinically severe. Severe falciparum malaria is a medical emergency that is associated with a high mortality, even when trea...

Full description

Bibliographic Details
Published in:Malaria Journal
Main Authors: García-Bujalance Silvia, Francisco Carolina, Rubio José M, Arribas José R, Gutierrez Avelino
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2012
Subjects:
Plasmodium falciparum
HIV
Imported malaria
Sequence analysis
Drug interaction
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1186/1475-2875-11-136
https://doaj.org/article/ed4adacc57314ec181bdd3373c89e4bc
Description
Summary:Abstract As HIV becomes a chronic infection, an increasing number of HIV-infected patients are travelling to malaria-endemic areas. Association of malaria with HIV/AIDS can be clinically severe. Severe falciparum malaria is a medical emergency that is associated with a high mortality, even when treated in an Intensive Care Unit. This article describes two cases of HIV-positive patients, who returned from malaria-endemic areas and presented a parasitaemia > 5% of erythrocytes and clinical signs of severe falciparum malaria, both with > 350 CD4 cell count/μl, absence of chemoprophylaxis and successful response. Factors like drug interactions and the possible implication of anti-malarial therapy bioavailability are all especially interesting in HIV-malaria co-infections.

Similar Items