Assessing Inflammatory Bowel Disease-Associated Antibodies in Caucasian and First Nations Cohorts

BACKGROUND: First Nation populations in Canada have a very low incidence of inflammatory bowel disease (IBD). Based on typical infections in this population, it is plausible that the First Nations react differently to microbial antigens with a different antibody response pattern, which may shed some...

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Bibliographic Details
Published in:Canadian Journal of Gastroenterology
Main Authors: Charles N Bernstein, Hani El-Gabalawy, Michael Sargent, Carol J Landers, Patricia Rawsthorne, Brenda Elias, Stephan R Targan
Format: Article in Journal/Newspaper
Language:English
Published: Hindawi Limited 2011
Subjects:
Diseases of the digestive system. Gastroenterology
RC799-869
Canada
First Nations
Online Access:https://doi.org/10.1155/2011/712350
https://doaj.org/article/e96466f0055945ac8b6ac69aca5fdacf
Description
Summary:BACKGROUND: First Nation populations in Canada have a very low incidence of inflammatory bowel disease (IBD). Based on typical infections in this population, it is plausible that the First Nations react differently to microbial antigens with a different antibody response pattern, which may shed some light as to why they experience a low rate of IBD.

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