Suspected vertical transmission of Chagas disease caused by DTU TcIV in an infection probably transmitted orally, during anoutbreak in the Brazilian Amazon

ABSTRACT This study describes difficulties in the monitoring of a child born during an oral outbreak of Chagas disease, in which there are several indications that the transmission occurred through the congenital route: 1. the mother was in the third trimester of pregnancy when she was infected; 2....

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Vera Lúcia Teixeira de Freitas, Helena Rangel Esper, Erika Shimoda Nakanishi, Mariana Ramos Piotto, João Guilherme Pontes Lima Assy, Olívia Campos Pinheiro Berreta, Renato do Carmo Said, Aluisio Augusto Cotrim Segurado, Noemia Barbosa Carvalho, Francisco Oscar de Siqueira França, Marta Heloísa Lopes
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2021
Subjects:
Acute Chagas disease
Child
Diagnosis
Trypanosoma cruzi
DTUs
Vertical transmission
Oral outbreak
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946202163048
https://doaj.org/article/e6a158dc107b41f8b579b30fc1021711
Description
Summary:ABSTRACT This study describes difficulties in the monitoring of a child born during an oral outbreak of Chagas disease, in which there are several indications that the transmission occurred through the congenital route: 1. the mother was in the third trimester of pregnancy when she was infected; 2. She presented high parasitemia at the time of delivery; 3. In both, the mother and her daughter, T. cruzi was classified as DTU TcIV. The parasites were not found in the blood at birth and the infection was detected only three months later in an asymptomatic infant. As the mother and her child live in a highly endemic area, vector transmission could not be excluded during this period.

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