Need for optimized dosages in the design of comparative clinical trials of anti-malarial drugs

Abstract We read with interest the publication on malaria treatment by Obonyo et al. (Malaria J 21:30, 2022). This commentary questions the methodology, especially the chosen time points of treatment outcome measures.

Bibliographic Details
Published in:	Malaria Journal
Main Authors:	Sanjeev Krishna, Peter G. Kremsner
Format:	Article in Journal/Newspaper
Language:	English
Published:	BMC 2022
Subjects:	Artemether–lumefantrine Children Clindamycin Kenya Malaria Quinine Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Arctic
Online Access:	https://doi.org/10.1186/s12936-022-04170-1 https://doaj.org/article/e456ec4ebd2f4a558bed8f5328ed1870

Description
Summary:	Abstract We read with interest the publication on malaria treatment by Obonyo et al. (Malaria J 21:30, 2022). This commentary questions the methodology, especially the chosen time points of treatment outcome measures.