Some hematimetric findings in human Giardia lambia infection Valores hematimétricos na infecção humana causada por Giardia lamblia

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Jairo Ivo dos Santos, Cidônia de Lourdes Vituri
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1996
• Subjects: Giardia lamblia; Giardiasis; Eosinophilia; Hematimetric parameters; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/S0036-46651996000200002; https://doaj.org/article/de5a997cd17c4fee870f41a60a4ca7cc

Up to now few reports about haematological alterations induced by Giardia lamblia infection have been described. Because there are questions on this matter still not answered, we carried out a study to evaluate some erythrometric and leucometric parameters in a sample that consisted of 55 patients exclusively infected with G. lamblia and of 55 sex and age matched parasite-free individuals. The haematological parameters evaluated were: mean corpuscular volume (MCV), hemoglobin concentration, and relative and absolute number of eosinophils and lymphocytes. No significant differences in the mean values of MCV, hemoglobin levels and absolute relative lymphocyte numbers between the two groups could be detected. When the giardiasis and control groups were separated by pediatric (0-18 years old) and adult (older than 18 years) classes, a very significant difference in both relative and absolute number of eosinophils in the adult class was observed. With respect of the pediatric class, no differences, either in relative and absolute number of eosinophils, could be observed. Our findings suggest that, during G. lamblia infection, some kind of parasite allergen(s) could be secreted and be responsible for the increasing of eosinophil counts in peripheral blood of adults. Até este momento poucos relatos de alterações hematológicas causadas pela Giardia lamblia têm sido descritos. Procuramos então avaliar alguns parâmetros hematológicos em pacientes infectados exclusivamente com G. lamblia (n=55), provenientes do Hospital Universitário, comparando-os com pacientes, pareados por sexo e idade, sem nenhum parasitismo (n=55). Foram avaliados: volume corpuscular médio (VCM), níveis de hemoglobina e contagem absoluta e relativa de eosinófilos e linfócitos. Não foram observadas diferenças significativas entre os valores médios de VCM, níveis de hemoglobina e contagem absoluta e relativa de linfócitos para os dois grupos estudados. No caso dos eosinófilos, tanto as contagens relativas quanto as absolutas diferiram significativamente ...