Detección de anticuerpos contra agentes virales y bacterias atípicas en el suero de pacientes con infección respiratoria, Estado Zulia- Venezuela, periodo 2005 – 2010

• Main Authors: Bermúdez F John Emmanuel, Gotera Z Jennifer Lucila, Mavares M Alibeth Rossana, Calles U Andrés David, Paredes L Cristina Rose, Pirela I Dariana Paoly, Duran M Anyelo Alberto, Valero C Nereida Josefina
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2014
• Subjects: Infección respiratoria; bacterias atípicas; virus respiratorios; IgM; Estado Zulia; Respiratory infection; atypical bacteria; respiratory viruses; State of Zulia; Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic
• Online Access: https://doaj.org/article/dce6d65cf71b4491bdec37bd99071c64

Abstract: The purpose of this study was to determine the presence of serum antibodies against respiratory viruses and atypical bacteria in patients with respiratory infections in the State of Zulia, Venezuela, between January 2005 and December 2010. Two-hundred eighty-three (283) serum samples from those patients were analyzed. Patients were classified according to age as: 1 to 23 months, 2 to 6 years, 7 to 14, 15 to 19, 20 to 40, 41 to 64 and 65 years old and over. Seric IgM against viral agents (Adenovirus, Parainfluenza 1, 2, 3, Influenza A and B and respiratory syncytial virus: RSV) and atypical bacteria (Mycoplasma pneumoniae, Legionella pneumophila serotype 1, Coxiella burnetii and Chlamydophila pneumoniae) were determined by indirect immunofluorescence. Of the 283 samples, 113 were seropositive; no co-infections were found. The most frequently found agent was RSV (27/113; 23.89%; p<0.01), followed by Legionella pneumophila serotype 1 (19/113; 16.81%; p<0.001). Adenovirus (16/113; 14.16%), Mycoplasma pneumoniae (15/113; 13.27%), Parainfluenza 1, 2 3 (14/113; 12.40%), Influenza A and B (13/113; 11.5%), Coxiella burnetii (6/113; 5.31%) and Chlamydophila pneumoniae (3/113; 2.65%) were less frequent. Young and middle-aged adults were the most affected. In conclusion, respiratory viruses cause a great part of the infections in the analyzed population; however, it is important to note the high frequency of atypical bacteria in the region. Resumen: El propósito de este estudio fue detectar anticuerpos contra virus respiratorios y bacterias atípicas en el suero de pacientes con infección respiratoria, en el Estado Zulia–Venezuela entre enero 2005 y diciembre 2010. Se analizaron 283 muestras de pacientes con sintomatología de infección respiratoria, clasificados en grupos etarios de 1-23 meses, 2-6, 7-14, 15-19, 20-40, 41-64 y 65 años de edad y más. La IgM sérica contra agentes virales (Adenovirus, Parainfluenza 1, 2, 3, Influenza A y B y Virus Sincicial Respiratorio) y bacterias atípicas (Mycoplasma ...