Phytochemistry of the essential oil of Melissa officinalis L. growing wild in Morocco: Preventive approach against nosocomial infections
Objective: To determine the phytochemical characterization and antibacterial activity of Melissa officinalis essential oil against bacteria responsible for nosocomial infections. Methods: The phytochemical characterization of essential oil was evaluated using gas chromatography-flame ionization dete...
| Published in: | Asian Pacific Journal of Tropical Biomedicine |
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| Main Authors: | , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015
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| Subjects: | |
| Online Access: | https://doi.org/10.1016/j.apjtb.2015.03.003 https://doaj.org/article/d78af829bd894b67acfbb8b95ff7bfb7 |
| Summary: | Objective: To determine the phytochemical characterization and antibacterial activity of Melissa officinalis essential oil against bacteria responsible for nosocomial infections. Methods: The phytochemical characterization of essential oil was evaluated using gas chromatography-flame ionization detector and gas chromatography-mass spectrometer analysis. Antibacterial activity of the oil was tested against four bacterial strains responsible for nosocomial infections: Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus and Citrobacter koseri using disc diffusion method. Results: Thirty three components were identified representing 89.30% of the total oil composition. The yield of essential oil was 0.4% and the predominant components were citronellal (14.40%), isogeraniol (6.40%), geraniol acetate (10.20%), nerol acetate (5.10%), caryophyllene (8.10%) and β-caryophyllene oxide (11.00%). Antibacterial activity of the oil showed the higher activity against all bacterial strains tested. Conclusions: The essential oil extracted from lemon balm can be used to clean the environment of reanimation polyvalent and anaesthesia service. |
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