Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi
Infection by Trypanosoma cruzi in mice depresses hepatic granuloma formation around Schistosoma mansoni eggs. This immunodepressive effect occurred in mice with Chagas' disease at the acute and/or chronic phases, granulomas being signijicantly smaller than those in Controls. Data suggest that C...
| Main Authors: | , , |
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| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
1986
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| Subjects: | |
| Online Access: | https://doaj.org/article/d4d0ab1583a248c3a752b5fb561eb5f4 |
| _version_ | 1821827808068894720 |
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| author | O. Genaro Z. Brener P.M.Z. Coelho |
| author_facet | O. Genaro Z. Brener P.M.Z. Coelho |
| author_sort | O. Genaro |
| collection | Directory of Open Access Journals: DOAJ Articles |
| description | Infection by Trypanosoma cruzi in mice depresses hepatic granuloma formation around Schistosoma mansoni eggs. This immunodepressive effect occurred in mice with Chagas' disease at the acute and/or chronic phases, granulomas being signijicantly smaller than those in Controls. Data suggest that Chagas ' disease depresses the delayed hypersensitivity immune response directly. A infecção de camundongos pelo Trypanosoma cruzi inibe a formação do granuloma hepático esquistossomótico. Este efeito imunodepressor ocorreu em camundongos com a fase aguda ou crônica da doença de Chagas, sendo os granulomas significativamente menores que nos animais controles. Os dados sugerem que a doença de Chagas deprime diretamente a imunidade celular. |
| format | Article in Journal/Newspaper |
| genre | Arctic |
| genre_facet | Arctic |
| geographic | Aguda Arctic |
| geographic_facet | Aguda Arctic |
| id | ftdoajarticles:oai:doaj.org/article:d4d0ab1583a248c3a752b5fb561eb5f4 |
| institution | Open Polar |
| language | English |
| long_lat | ENVELOPE(-26.750,-26.750,-76.150,-76.150) |
| op_collection_id | ftdoajarticles |
| op_relation | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821986000100008 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/d4d0ab1583a248c3a752b5fb561eb5f4 |
| op_source | Revista da Sociedade Brasileira de Medicina Tropical, Vol 19, Iss 1, Pp 35-37 (1986) |
| publishDate | 1986 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | openpolar |
| spelling | ftdoajarticles:oai:doaj.org/article:d4d0ab1583a248c3a752b5fb561eb5f4 2025-01-16T20:32:43+00:00 Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi O. Genaro Z. Brener P.M.Z. Coelho 1986-03-01T00:00:00Z https://doaj.org/article/d4d0ab1583a248c3a752b5fb561eb5f4 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821986000100008 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/d4d0ab1583a248c3a752b5fb561eb5f4 Revista da Sociedade Brasileira de Medicina Tropical, Vol 19, Iss 1, Pp 35-37 (1986) Schistosoma mansoni Imunodepressão Granuloma Trypanosoma cruzi Immunodepression Arctic medicine. Tropical medicine RC955-962 article 1986 ftdoajarticles 2022-12-30T23:18:18Z Infection by Trypanosoma cruzi in mice depresses hepatic granuloma formation around Schistosoma mansoni eggs. This immunodepressive effect occurred in mice with Chagas' disease at the acute and/or chronic phases, granulomas being signijicantly smaller than those in Controls. Data suggest that Chagas ' disease depresses the delayed hypersensitivity immune response directly. A infecção de camundongos pelo Trypanosoma cruzi inibe a formação do granuloma hepático esquistossomótico. Este efeito imunodepressor ocorreu em camundongos com a fase aguda ou crônica da doença de Chagas, sendo os granulomas significativamente menores que nos animais controles. Os dados sugerem que a doença de Chagas deprime diretamente a imunidade celular. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Aguda ENVELOPE(-26.750,-26.750,-76.150,-76.150) Arctic |
| spellingShingle | Schistosoma mansoni Imunodepressão Granuloma Trypanosoma cruzi Immunodepression Arctic medicine. Tropical medicine RC955-962 O. Genaro Z. Brener P.M.Z. Coelho Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi |
| title | Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi |
| title_full | Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi |
| title_fullStr | Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi |
| title_full_unstemmed | Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi |
| title_short | Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi |
| title_sort | schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by trypanosoma cruzi |
| topic | Schistosoma mansoni Imunodepressão Granuloma Trypanosoma cruzi Immunodepression Arctic medicine. Tropical medicine RC955-962 |
| topic_facet | Schistosoma mansoni Imunodepressão Granuloma Trypanosoma cruzi Immunodepression Arctic medicine. Tropical medicine RC955-962 |
| url | https://doaj.org/article/d4d0ab1583a248c3a752b5fb561eb5f4 |