Antimicrobial Susceptibility and b-Lactamase Production in Strains of Neisseria gonorrhoeae Isolated in Patients from the University Hospital “Dr. Manuel Núñez Tovar”, Monagas State-Venezuela

In order to determine the patterns of antimicrobial susceptibility and beta-lactamase production, 60 patients with sexually transmitted diseases were studied from the University Hospital “Dr. Manuel Nuñez Tovar” jurisdiction in Monagas State. Thirty-five N. gonorrhoeae strains (58,30%) were isolated...

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Bibliographic Details
Main Authors: J Lanz, H De Freitas, J Betancourt, N Núñez, W Velásquez
Format: Article in Journal/Newspaper
Language:English
Spanish
Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2004
Subjects:
Neisseria gonorrhoeae
susceptibilidad
beta lactamasa
antimicrobianos
resistencia
gonorrea
Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Arctic
Núñez
Online Access:https://doaj.org/article/d11f4e42d6ad4f85a3738be7d0b5c393
Description
Summary:In order to determine the patterns of antimicrobial susceptibility and beta-lactamase production, 60 patients with sexually transmitted diseases were studied from the University Hospital “Dr. Manuel Nuñez Tovar” jurisdiction in Monagas State. Thirty-five N. gonorrhoeae strains (58,30%) were isolated, and they were grouped according to antimicrobial susceptibility and beta-lactamase production. A high resistance rate to penicillin (94.24%) and to tetracycline (97.14%) was detected. Out of the 33 N. gonorrhoeae strains resistant to penicillin, 15 (45.45%) did not produce beta-lactamase. On the other hand, in vitro sensitivity of N. gonorrhoeae to cefepime, cefoxitin and ceftriaxone was 97.14%, 94.29%, and 80.50%, respectively . In relation to the susceptibility to ofloxacin, it was found that 97,14% of the strains of N. gonorrhoeae showed sensitivity a this antimicrobial. treatment.

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